Li R - Search Results

1

Albumin nanoparticle containing a PI3Kγ inhibitor and paclitaxel in combination with α-PD1 induces tumor remission of breast cancer in mice.

Song Y, Bugada L, Li R, Hu H, Zhang L, Li C, Yuan H, Rajanayake KK, Truchan NA, Wen F, Gao W, Sun D. Song Y, et al. Among authors: li c, li r. Sci Transl Med. 2022 May 4;14(643):eabl3649. doi: 10.1126/scitranslmed.abl3649. Epub 2022 May 4. Sci Transl Med. 2022. PMID: 35507675 Free PMC article.

2

EEDi-5285: An Exceptionally Potent, Efficacious, and Orally Active Small-Molecule Inhibitor of Embryonic Ectoderm Development.

Rej RK, Wang C, Lu J, Wang M, Petrunak E, Zawacki KP, McEachern D, Fernandez-Salas E, Yang CY, Wang L, Li R, Chinnaswamy K, Wen B, Sun D, Stuckey J, Zhou Y, Chen J, Tang G, Wang S. Rej RK, et al. Among authors: li r. J Med Chem. 2020 Jul 9;63(13):7252-7267. doi: 10.1021/acs.jmedchem.0c00479. Epub 2020 Jun 24. J Med Chem. 2020. PMID: 32580550 Free PMC article.

3

SD-91 as A Potent and Selective STAT3 Degrader Capable of Achieving Complete and Long-Lasting Tumor Regression.

Zhou H, Bai L, Xu R, McEachern D, Chinnaswamy K, Li R, Wen B, Wang M, Yang CY, Meagher JL, Sun D, Stuckey JA, Wang S. Zhou H, et al. Among authors: li r. ACS Med Chem Lett. 2021 May 10;12(6):996-1004. doi: 10.1021/acsmedchemlett.1c00155. eCollection 2021 Jun 10. ACS Med Chem Lett. 2021. PMID: 34141084 Free PMC article.

4

Discovery of EEDi-5273 as an Exceptionally Potent and Orally Efficacious EED Inhibitor Capable of Achieving Complete and Persistent Tumor Regression.

Rej RK, Wang C, Lu J, Wang M, Petrunak E, Zawacki KP, McEachern D, Yang CY, Wang L, Li R, Chinnaswamy K, Wen B, Sun D, Stuckey JA, Zhou Y, Chen J, Tang G, Wang S. Rej RK, et al. Among authors: li r. J Med Chem. 2021 Oct 14;64(19):14540-14556. doi: 10.1021/acs.jmedchem.1c01059. Epub 2021 Oct 6. J Med Chem. 2021. PMID: 34613724 Free PMC article.

5

Phospholipid nanoparticles: Therapeutic potentials against atherosclerosis via reducing cholesterol crystals and inhibiting inflammation.

Luo Y, Guo Y, Wang H, Yu M, Hong K, Li D, Li R, Wen B, Hu D, Chang L, Zhang J, Yang B, Sun D, Schwendeman AS, Eugene Chen Y. Luo Y, et al. Among authors: li d, li r. EBioMedicine. 2021 Dec;74:103725. doi: 10.1016/j.ebiom.2021.103725. Epub 2021 Dec 6. EBioMedicine. 2021. PMID: 34879325 Free PMC article.

6

Optimization of the Prodrug Moiety of Remdesivir to Improve Lung Exposure/Selectivity and Enhance Anti-SARS-CoV-2 Activity.

Hu H, Mady Traore MD, Li R, Yuan H, He M, Wen B, Gao W, Jonsson CB, Fitzpatrick EA, Sun D. Hu H, et al. Among authors: li r. J Med Chem. 2022 Sep 22;65(18):12044-12054. doi: 10.1021/acs.jmedchem.2c00758. Epub 2022 Sep 7. J Med Chem. 2022. PMID: 36070561

7

Morphomics-informed population pharmacokinetic and physiologically-based pharmacokinetic modeling to optimize cefazolin surgical prophylaxis.

Liu S, Matvekas A, Naimi T, Ghanem A, Li R, Rajanayake K, Derstine B, Ross B, Sullivan J, Yun HG, Regenbogen S, Byrn J, Su G, Wang S, Pai MP. Liu S, et al. Among authors: li r. Pharmacotherapy. 2024 Jan;44(1):77-86. doi: 10.1002/phar.2878. Epub 2023 Sep 29. Pharmacotherapy. 2024. PMID: 37728152

8

Bioanalysis of six antibiotics from volumetric microsamples: a new tool for precision dosing in critically ill children.

Takyi-Williams J, Leino AD, Li R, Downes KJ, Zuppa AF, Bwint A, Wen B, Sun D, Scheetz MH, Pai MP. Takyi-Williams J, et al. Among authors: li r. Bioanalysis. 2024 Jan;16(1):19-31. doi: 10.4155/bio-2023-0171. Epub 2023 Nov 22. Bioanalysis. 2024. PMID: 37991215

9

Discovery of CBPD-268 as an Exceptionally Potent and Orally Efficacious CBP/p300 PROTAC Degrader Capable of Achieving Tumor Regression.

Chen Z, Wang M, Wu D, Bai L, Xu T, Metwally H, Wang Y, McEachern D, Zhao L, Li R, Takyi-Williams J, Wang M, Wang L, Li Q, Wen B, Sun D, Wang S. Chen Z, et al. Among authors: li q, li r. J Med Chem. 2024 Apr 11;67(7):5275-5304. doi: 10.1021/acs.jmedchem.3c02124. Epub 2024 Mar 13. J Med Chem. 2024. PMID: 38477974

10

Developing a SWATH capillary LC-MS/MS method for simultaneous therapeutic drug monitoring and untargeted metabolomics analysis of neonatal plasma.

Xiao J, Shi J, Li R, Her L, Wang X, Li J, Sorensen MJ, Bhatt-Mehta V, Zhu HJ. Xiao J, et al. Among authors: li j, li r. J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Aug 1;1179:122865. doi: 10.1016/j.jchromb.2021.122865. Epub 2021 Jul 27. J Chromatogr B Analyt Technol Biomed Life Sci. 2021. PMID: 34365292 Free PMC article.

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