Li M - Search Results

1

Discovery of CDK5 Inhibitors through Structure-Guided Approach.

Khair NZ, Lenjisa JL, Tadesse S, Kumarasiri M, Basnet SKC, Mekonnen LB, Li M, Diab S, Sykes MJ, Albrecht H, Milne R, Wang S. Khair NZ, et al. Among authors: li m. ACS Med Chem Lett. 2019 Mar 20;10(5):786-791. doi: 10.1021/acsmedchemlett.9b00029. eCollection 2019 May 9. ACS Med Chem Lett. 2019. PMID: 31098000 Free PMC article.

2

Synthesis and evaluation of 2'H-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine]-1',5'-dione derivatives as Mnk inhibitors.

Abdelaziz AM, Basnet SKC, Islam S, Li M, Tadesse S, Albrecht H, Gerber C, Yu M, Wang S. Abdelaziz AM, et al. Among authors: li m. Bioorg Med Chem Lett. 2019 Sep 15;29(18):2650-2654. doi: 10.1016/j.bmcl.2019.07.043. Epub 2019 Jul 23. Bioorg Med Chem Lett. 2019. PMID: 31362920

3

Potent and orally bioavailable CDK8 inhibitors: Design, synthesis, structure-activity relationship analysis and biological evaluation.

Yu M, Teo T, Yang Y, Li M, Long Y, Philip S, Noll B, Heinemann GK, Diab S, Eldi P, Mekonnen L, Anshabo AT, Rahaman MH, Milne R, Hayball JD, Wang S. Yu M, et al. Among authors: li m. Eur J Med Chem. 2021 Mar 15;214:113248. doi: 10.1016/j.ejmech.2021.113248. Epub 2021 Feb 3. Eur J Med Chem. 2021. PMID: 33571827

4

Discovery of a potent, highly selective, and orally bioavailable inhibitor of CDK8 through a structure-based optimisation.

Yu M, Long Y, Yang Y, Li M, Teo T, Noll B, Philip S, Wang S. Yu M, et al. Among authors: li m. Eur J Med Chem. 2021 Jun 5;218:113391. doi: 10.1016/j.ejmech.2021.113391. Epub 2021 Mar 26. Eur J Med Chem. 2021. PMID: 33823391

5

An Orally Bioavailable and Highly Efficacious Inhibitor of CDK9/FLT3 for the Treatment of Acute Myeloid Leukemia.

Anshabo AT, Bantie L, Diab S, Lenjisa J, Kebede A, Long Y, Heinemann G, Karanjia J, Noll B, Basnet SKC, Li M, Milne R, Albrecht H, Wang S. Anshabo AT, et al. Among authors: li m. Cancers (Basel). 2022 Feb 22;14(5):1113. doi: 10.3390/cancers14051113. Cancers (Basel). 2022. PMID: 35267421 Free PMC article.

6

Ceramide-induced integrated stress response overcomes Bcl-2 inhibitor resistance in acute myeloid leukemia.

Lewis AC, Pope VS, Tea MN, Li M, Nwosu GO, Nguyen TM, Wallington-Beddoe CT, Moretti PAB, Anderson D, Creek DJ, Costabile M, Ali SR, Thompson-Peach CAL, Dredge BK, Bert AG, Goodall GJ, Ekert PG, Brown AL, D'Andrea R, Robinson N, Pitman MR, Thomas D, Ross DM, Gliddon BL, Powell JA, Pitson SM. Lewis AC, et al. Among authors: li m. Blood. 2022 Jun 30;139(26):3737-3751. doi: 10.1182/blood.2021013277. Blood. 2022. PMID: 35443029 Free PMC article.

7

Resensitising proteasome inhibitor-resistant myeloma with sphingosine kinase 2 inhibition.

Bennett MK, Li M, Tea MN, Pitman MR, Toubia J, Wang PP, Anderson D, Creek DJ, Orlowski RZ, Gliddon BL, Powell JA, Wallington-Beddoe CT, Pitson SM. Bennett MK, et al. Among authors: li m. Neoplasia. 2022 Jan;24(1):1-11. doi: 10.1016/j.neo.2021.11.009. Epub 2021 Nov 23. Neoplasia. 2022. PMID: 34826777 Free PMC article.

8

An orthotopic syngeneic mouse model of bortezomib-resistant multiple myeloma.

Li M, Bennett MK, Toubia J, Pope VS, Tea MN, Tamang S, Samuel MS, Anderson PH, Gliddon BL, Powell JA, Pitson SM. Li M, et al. Br J Haematol. 2024 Feb;204(2):566-570. doi: 10.1111/bjh.19240. Epub 2023 Dec 5. Br J Haematol. 2024. PMID: 38053270

9

Ceritinib Enhances the Efficacy of Substrate Chemotherapeutic Agent in Human ABCB1-Overexpressing Leukemia Cells In Vitro, In Vivo and Ex-Vivo.

Yang L, Li M, Wang F, Zhen C, Luo M, Fang X, Zhang H, Zhang J, Li Q, Fu L. Yang L, et al. Among authors: li m, li q. Cell Physiol Biochem. 2018;46(6):2487-2499. doi: 10.1159/000489655. Epub 2018 May 5. Cell Physiol Biochem. 2018. PMID: 29742496 Free article.

10

Alkyl Chains Tune Molecular Orientations to Enable Dual Passivation in Inverted Perovskite Solar Cells.

Liu J, Chen J, Xie L, Yang S, Meng Y, Li M, Xiao C, Zhu J, Do H, Zhang J, Yang M, Ge Z. Liu J, et al. Among authors: li m. Angew Chem Int Ed Engl. 2024 May 9:e202403610. doi: 10.1002/anie.202403610. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 38721714

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