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Safety and efficacy of a biodegradable implant releasing tenofovir alafenamide for vaginal protection in a macaque model.
Massud I, Krovi A, Nishiura K, Ruone S, Li L, Holder A, Gary J, Mills P, Mitchell J, Khalil G, Pan Y, Luecke E, Gatto G, Heneine W, García-Lerma JG, Johnson L, van der Straten A, Dobard C. Massud I, et al. Among authors: li l. J Antimicrob Chemother. 2022 Oct 28;77(11):2964-2971. doi: 10.1093/jac/dkac252. J Antimicrob Chemother. 2022. PMID: 35913838 Free PMC article.
Comparative Pharmacokinetics and Local Tolerance of Tenofovir Alafenamide (TAF) From Subcutaneous Implant in Rabbits, Dogs, and Macaques.
Gatto GJ, Krovi A, Li L, Massud I, Holder A, Gary J, Mills P, Mitchell J, Luecke E, Demkovich ZR, Heneine W, García-Lerma JG, Marzinke MA, Brand RM, Dobard CW, Johnson LM, Van Der Straten A. Gatto GJ, et al. Among authors: li l. Front Pharmacol. 2022 Jul 19;13:923954. doi: 10.3389/fphar.2022.923954. eCollection 2022. Front Pharmacol. 2022. PMID: 35928266 Free PMC article.
Pharmacokinetic Study of Islatravir and Etonogestrel Implants in Macaques.
Daly MB, Wong-Sam A, Li L, Krovi A, Gatto GJ, Norton C, Luecke EH, Mrotz V, Forero C, Cottrell ML, Schauer AP, Gary J, Nascimento-Seixas J, Mitchell J, van der Straten A, Heneine W, García-Lerma JG, Dobard CW, Johnson LM. Daly MB, et al. Among authors: li l. Pharmaceutics. 2023 Nov 26;15(12):2676. doi: 10.3390/pharmaceutics15122676. Pharmaceutics. 2023. PMID: 38140017 Free PMC article.
Pharmacokinetic Modeling to Guide Preclinical Development of an Islatravir-Eluting Reservoir-Style Biodegradable Implant for Long-Acting HIV PrEP.
Kinsale TS, Cottrell ML, Li L, Brand R, Gatto G, Luecke E, Norton C, Krovi A, Dumond JB, Rao G, Yeshwante S, Van Horne B, Van Der Straten A, Kashuba ADM, Johnson LM. Kinsale TS, et al. Among authors: li l. Pharmaceutics. 2024 Jan 30;16(2):201. doi: 10.3390/pharmaceutics16020201. Pharmaceutics. 2024. PMID: 38399255 Free PMC article.
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