Li L - Search Results

1

Bioequivalence of saxagliptin/metformin extended-release (XR) fixed-dose combination tablets and single-component saxagliptin and metformin XR tablets in healthy adult subjects.

Boulton DW, Smith CH, Li L, Huang J, Tang A, LaCreta FP. Boulton DW, et al. Among authors: li l. Clin Drug Investig. 2011;31(9):619-30. doi: 10.2165/11590290-000000000-00000. Clin Drug Investig. 2011. PMID: 21819160 Clinical Trial.

2

Saxagliptin, a potent, selective inhibitor of DPP-4, does not alter the pharmacokinetics of three oral antidiabetic drugs (metformin, glyburide or pioglitazone) in healthy subjects.

Patel CG, Kornhauser D, Vachharajani N, Komoroski B, Brenner E, Handschuh del Corral M, Li L, Boulton DW. Patel CG, et al. Among authors: li l. Diabetes Obes Metab. 2011 Jul;13(7):604-14. doi: 10.1111/j.1463-1326.2011.01381.x. Diabetes Obes Metab. 2011. PMID: 21332626 Clinical Trial.

3

Effect of saxagliptin on the pharmacokinetics of the active components of Ortho-Cyclen(®), a combined oral contraceptive containing ethinyl estradiol and norgestimate, in healthy women.

Upreti VV, Hsiang CB, Li L, Xu X, LaCreta FP, Boulton DW. Upreti VV, et al. Among authors: li l. Diabetes Obes Metab. 2012 Dec;14(12):1155-7. doi: 10.1111/j.1463-1326.2012.01635.x. Epub 2012 Jul 9. Diabetes Obes Metab. 2012. PMID: 22776778 Clinical Trial.

4

Dapagliflozin, a novel SGLT2 inhibitor, induces dose-dependent glucosuria in healthy subjects.

Komoroski B, Vachharajani N, Boulton D, Kornhauser D, Geraldes M, Li L, Pfister M. Komoroski B, et al. Among authors: li l. Clin Pharmacol Ther. 2009 May;85(5):520-6. doi: 10.1038/clpt.2008.251. Epub 2009 Jan 7. Clin Pharmacol Ther. 2009. PMID: 19129748 Clinical Trial.

5

Dapagliflozin, a novel, selective SGLT2 inhibitor, improved glycemic control over 2 weeks in patients with type 2 diabetes mellitus.

Komoroski B, Vachharajani N, Feng Y, Li L, Kornhauser D, Pfister M. Komoroski B, et al. Among authors: li l. Clin Pharmacol Ther. 2009 May;85(5):513-9. doi: 10.1038/clpt.2008.250. Epub 2009 Jan 7. Clin Pharmacol Ther. 2009. PMID: 19129749 Clinical Trial.

6

Comparison of changes in the lipid profile of postmenopausal women with early stage breast cancer treated with exemestane or letrozole.

Bell LN, Nguyen AT, Li L, Desta Z, Henry NL, Hayes DF, Wolff AC, Stearns V, Storniolo AM, Flockhart DA; Consortium on Breast Cancer Pharmacogenomics (COBRA). Bell LN, et al. Among authors: li l. J Clin Pharmacol. 2012 Dec;52(12):1852-60. doi: 10.1177/0091270011424153. Epub 2011 Dec 15. J Clin Pharmacol. 2012. PMID: 22174434 Free PMC article. Clinical Trial.

7

Cytochrome P450 3A5 genotype is associated with verapamil response in healthy subjects.

Jin Y, Wang YH, Miao J, Li L, Kovacs RJ, Marunde R, Hamman MA, Philips S, Hilligoss J, Hall SD. Jin Y, et al. Among authors: li l. Clin Pharmacol Ther. 2007 Nov;82(5):579-85. doi: 10.1038/sj.clpt.6100208. Epub 2007 Apr 18. Clin Pharmacol Ther. 2007. PMID: 17443134

8

Rifampin enhances cytochrome P450 (CYP) 2B6-mediated efavirenz 8-hydroxylation in healthy volunteers.

Cho DY, Shen JH, Lemler SM, Skaar TC, Li L, Blievernicht J, Zanger UM, Kim KB, Shin JG, Flockhart DA, Desta Z. Cho DY, et al. Among authors: li l. Drug Metab Pharmacokinet. 2016 Apr;31(2):107-16. doi: 10.1016/j.dmpk.2015.07.002. Epub 2015 Jul 29. Drug Metab Pharmacokinet. 2016. PMID: 27053325 Free PMC article. Clinical Trial.

9

Variability of heart rate correction methods for the QT interval.

Desai M, Li L, Desta Z, Malik M, Flockhart D. Desai M, et al. Among authors: li l. Br J Clin Pharmacol. 2003 Jun;55(6):511-7. doi: 10.1046/j.1365-2125.2003.01791.x. Br J Clin Pharmacol. 2003. PMID: 12814443 Free PMC article. Clinical Trial.

10

Computational approaches that predict metabolic intermediate complex formation with CYP3A4 (+b5).

Jones DR, Ekins S, Li L, Hall SD. Jones DR, et al. Among authors: li l. Drug Metab Dispos. 2007 Sep;35(9):1466-75. doi: 10.1124/dmd.106.014613. Epub 2007 May 30. Drug Metab Dispos. 2007. PMID: 17537872

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