Li J - Search Results

1

Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses.

Zhou X, Zhao C, Xu H, Xu Y, Zhan L, Wang P, He J, Lu T, Gu Y, Yang Y, Xu C, Chen Y, Liu Y, Zeng Y, Tian F, Chen Q, Xie X, Liu J, Hu H, Li J, Zheng Y, Guo J, Gao Z. Zhou X, et al. Among authors: li j. Nat Chem Biol. 2024 Feb 14. doi: 10.1038/s41589-024-01555-y. Online ahead of print. Nat Chem Biol. 2024. PMID: 38355723

2

Discovery of a novel CCR5 antagonist lead compound through fragment assembly.

Liu Y, Zhou E, Yu K, Zhu J, Zhang Y, Xie X, Li J, Jiang H. Liu Y, et al. Among authors: li j. Molecules. 2008 Oct 1;13(10):2426-41. doi: 10.3390/molecules13102426. Molecules. 2008. PMID: 18830165 Free PMC article.

3

Small-molecule targeting of a diapophytoene desaturase inhibits S. aureus virulence.

Chen F, Di H, Wang Y, Cao Q, Xu B, Zhang X, Yang N, Liu G, Yang CG, Xu Y, Jiang H, Lian F, Zhang N, Li J, Lan L. Chen F, et al. Among authors: li j. Nat Chem Biol. 2016 Mar;12(3):174-9. doi: 10.1038/nchembio.2003. Epub 2016 Jan 18. Nat Chem Biol. 2016. PMID: 26780405

4

Novel Vilazodone-Tacrine Hybrids as Potential Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease Accompanied with Depression: Design, Synthesis, and Biological Evaluation.

Li X, Wang H, Xu Y, Liu W, Gong Q, Wang W, Qiu X, Zhu J, Mao F, Zhang H, Li J. Li X, et al. Among authors: li j. ACS Chem Neurosci. 2017 Dec 20;8(12):2708-2721. doi: 10.1021/acschemneuro.7b00259. Epub 2017 Sep 19. ACS Chem Neurosci. 2017. PMID: 28872831

5

TRPA1 channel mediates organophosphate-induced delayed neuropathy.

Ding Q, Fang S, Chen X, Wang Y, Li J, Tian F, Xu X, Attali B, Xie X, Gao Z. Ding Q, et al. Among authors: li j. Cell Discov. 2017 Aug 1;3:17024. doi: 10.1038/celldisc.2017.24. eCollection 2017. Cell Discov. 2017. PMID: 28894590 Free PMC article.

6

Design, Synthesis, and Biological Evaluation of Orally Available First-Generation Dual-Target Selective Inhibitors of Acetylcholinesterase (AChE) and Phosphodiesterase 5 (PDE5) for the Treatment of Alzheimer's Disease.

Mao F, Wang H, Ni W, Zheng X, Wang M, Bao K, Ling D, Li X, Xu Y, Zhang H, Li J. Mao F, et al. Among authors: li j, li x. ACS Chem Neurosci. 2018 Feb 21;9(2):328-345. doi: 10.1021/acschemneuro.7b00345. Epub 2017 Nov 9. ACS Chem Neurosci. 2018. PMID: 29068218

7

Rational Design of Novel Selective Dual-Target Inhibitors of Acetylcholinesterase and Monoamine Oxidase B as Potential Anti-Alzheimer's Disease Agents.

Xu Y, Zhang J, Wang H, Mao F, Bao K, Liu W, Zhu J, Li X, Zhang H, Li J. Xu Y, et al. Among authors: li j, li x. ACS Chem Neurosci. 2019 Jan 16;10(1):482-496. doi: 10.1021/acschemneuro.8b00357. Epub 2018 Aug 29. ACS Chem Neurosci. 2019. PMID: 30110536

8

Targeting virulence factors as an antimicrobial approach: Pigment inhibitors.

Ni S, Li B, Xu Y, Mao F, Li X, Lan L, Zhu J, Li J. Ni S, et al. Among authors: li j, li x, li b. Med Res Rev. 2020 Jan;40(1):293-338. doi: 10.1002/med.21621. Epub 2019 Jul 2. Med Res Rev. 2020. PMID: 31267561 Review.

9

Drug repositioning by prediction of drug's anatomical therapeutic chemical code via network-based inference approaches.

Peng Y, Wang M, Xu Y, Wu Z, Wang J, Zhang C, Liu G, Li W, Li J, Tang Y. Peng Y, et al. Among authors: li j, li w. Brief Bioinform. 2021 Mar 22;22(2):2058-2072. doi: 10.1093/bib/bbaa027. Brief Bioinform. 2021. PMID: 32221552

10

Discovery of nitazoxanide-based derivatives as autophagy activators for the treatment of Alzheimer's disease.

Li X, Lu J, Xu Y, Wang J, Qiu X, Fan L, Li B, Liu W, Mao F, Zhu J, Shen X, Li J. Li X, et al. Among authors: li j, li b. Acta Pharm Sin B. 2020 Apr;10(4):646-666. doi: 10.1016/j.apsb.2019.07.006. Epub 2019 Jul 29. Acta Pharm Sin B. 2020. PMID: 32322468 Free PMC article.

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