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Synergistic activation of the insulin receptor via two distinct sites.
Li J, Park J, Mayer JP, Webb KJ, Uchikawa E, Wu J, Liu S, Zhang X, Stowell MHB, Choi E, Bai XC. Li J, et al. Nat Struct Mol Biol. 2022 Apr;29(4):357-368. doi: 10.1038/s41594-022-00750-6. Epub 2022 Mar 31. Nat Struct Mol Biol. 2022. PMID: 35361965 Free PMC article.
Activation of the insulin receptor by an insulin mimetic peptide.
Park J, Li J, Mayer JP, Ball KA, Wu J, Hall C, Accili D, Stowell MHB, Bai XC, Choi E. Park J, et al. Among authors: li j. Nat Commun. 2022 Sep 23;13(1):5594. doi: 10.1038/s41467-022-33274-0. Nat Commun. 2022. PMID: 36151101 Free PMC article.
Activation of human STING by a molecular glue-like compound.
Li J, Canham SM, Wu H, Henault M, Chen L, Liu G, Chen Y, Yu G, Miller HR, Hornak V, Brittain SM, Michaud GA, Tutter A, Broom W, Digan ME, McWhirter SM, Sivick KE, Pham HT, Chen CH, Tria GS, McKenna JM, Schirle M, Mao X, Nicholson TB, Wang Y, Jenkins JL, Jain RK, Tallarico JA, Patel SJ, Zheng L, Ross NT, Cho CY, Zhang X, Bai XC, Feng Y. Li J, et al. Nat Chem Biol. 2024 Mar;20(3):365-372. doi: 10.1038/s41589-023-01434-y. Epub 2023 Oct 12. Nat Chem Biol. 2024. PMID: 37828400 Free PMC article.
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