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Conjugation of a peptide to an antibody engineered with free cysteines dramatically improves half-life and activity.
Camacho RC, You S, D'Aquino KE, Li W, Wang Y, Gunnet J, Littrell J, Qi JS, Kang L, Jian W, MacDonald M, Tat T, Steiner D, Zhang YM, Lanter J, Patch R, Zhang R, Li J, Edavettal S, Edwards W, Dinh T, Wang LY, Connor J, Hunter M, Chi E, Swanson RV, Leonard JN, Case MA. Camacho RC, et al. Among authors: li j, li w. MAbs. 2020 Jan-Dec;12(1):1794687. doi: 10.1080/19420862.2020.1794687. MAbs. 2020. PMID: 32744157 Free PMC article.
Design, synthesis and preclinical evaluation of bio-conjugated amylinomimetic peptides as long-acting amylin receptor agonists.
Patch RJ, Zhang R, Edavettal S, Macielag MJ, Eckardt AJ, Li J, Rives ML, Edwards W, Hinke SA, Qiu X, Jian W, Libiger O, Zheng S, Jeyaseelan J, Liang Y, Rangwala SM, Leonard JN, Hornby P. Patch RJ, et al. Among authors: li j. Eur J Med Chem. 2022 Jun 5;236:114330. doi: 10.1016/j.ejmech.2022.114330. Epub 2022 Apr 4. Eur J Med Chem. 2022. PMID: 35436670
Novel Quantitative Contrast Sensitivity Function Enhances the Prediction of Treatment Outcome and Recurrence in Amblyopia.
Liu J, Huang C, Cotter SA, Chan LYL, Yu Y, Jia Y, Ye Q, Feng L, Yao Y, Jiang R, Xiao C, Xu Z, Zhuang Y, He Y, Zhou Y, Chen X, Yuan J, Wen Y, Yu W, Pang Y, Lu ZL, Thompson B, Li J. Liu J, et al. Among authors: li j. Invest Ophthalmol Vis Sci. 2024 May 1;65(5):31. doi: 10.1167/iovs.65.5.31. Invest Ophthalmol Vis Sci. 2024. PMID: 38771572
178,498 results
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