Li H - Search Results

1

Inhibiting de novo ceramide synthesis restores mitochondrial and protein homeostasis in muscle aging.

Lima TI, Laurila PP, Wohlwend M, Morel JD, Goeminne LJE, Li H, Romani M, Li X, Oh CM, Park D, Rodríguez-López S, Ivanisevic J, Gallart-Ayala H, Crisol B, Delort F, Batonnet-Pichon S, Silveira LR, Sankabattula Pavani Veera Venkata L, Padala AK, Jain S, Auwerx J. Lima TI, et al. Among authors: li h, li x. Sci Transl Med. 2023 May 17;15(696):eade6509. doi: 10.1126/scitranslmed.ade6509. Epub 2023 May 17. Sci Transl Med. 2023. PMID: 37196064

2

NAD⁺ boosting reduces age-associated amyloidosis and restores mitochondrial homeostasis in muscle.

Romani M, Sorrentino V, Oh CM, Li H, de Lima TI, Zhang H, Shong M, Auwerx J. Romani M, et al. Among authors: li h. Cell Rep. 2021 Jan 19;34(3):108660. doi: 10.1016/j.celrep.2020.108660. Cell Rep. 2021. PMID: 33472069 Free PMC article.

3

Urolithin A improves muscle function by inducing mitophagy in muscular dystrophy.

Luan P, D'Amico D, Andreux PA, Laurila PP, Wohlwend M, Li H, Imamura de Lima T, Place N, Rinsch C, Zanou N, Auwerx J. Luan P, et al. Among authors: li h. Sci Transl Med. 2021 Apr 7;13(588):eabb0319. doi: 10.1126/scitranslmed.abb0319. Sci Transl Med. 2021. PMID: 33827972

4

Mouse Systems Genetics as a Prelude to Precision Medicine.

Li H, Auwerx J. Li H, et al. Trends Genet. 2020 Apr;36(4):259-272. doi: 10.1016/j.tig.2020.01.004. Epub 2020 Feb 6. Trends Genet. 2020. PMID: 32037011 Free PMC article. Review.

5

Integrative systems analysis identifies genetic and dietary modulators of bile acid homeostasis.

Li H, Perino A, Huang Q, Von Alvensleben GVG, Banaei-Esfahani A, Velazquez-Villegas LA, Gariani K, Korbelius M, Bou Sleiman M, Imbach J, Sun Y, Li X, Bachmann A, Goeminne LJE, Gallart-Ayala H, Williams EG, Ivanisevic J, Auwerx J, Schoonjans K. Li H, et al. Among authors: li x. Cell Metab. 2022 Oct 4;34(10):1594-1610.e4. doi: 10.1016/j.cmet.2022.08.015. Epub 2022 Sep 12. Cell Metab. 2022. PMID: 36099916 Free PMC article.

6

The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging.

D'Amico D, Mottis A, Potenza F, Sorrentino V, Li H, Romani M, Lemos V, Schoonjans K, Zamboni N, Knott G, Schneider BL, Auwerx J. D'Amico D, et al. Among authors: li h. Mol Cell. 2019 Feb 21;73(4):775-787.e10. doi: 10.1016/j.molcel.2018.11.034. Epub 2019 Jan 11. Mol Cell. 2019. PMID: 30642763 Free PMC article.

7

The transcriptional coactivator CBP/p300 is an evolutionarily conserved node that promotes longevity in response to mitochondrial stress.

Li TY, Sleiman MB, Li H, Gao AW, Mottis A, Bachmann AM, El Alam G, Li X, Goeminne LJE, Schoonjans K, Auwerx J. Li TY, et al. Among authors: li h, li x. Nat Aging. 2021 Feb;1(2):165-178. doi: 10.1038/s43587-020-00025-z. Epub 2021 Feb 8. Nat Aging. 2021. PMID: 33718883 Free PMC article.

8

Cross-species functional modules link proteostasis to human normal aging.

Komljenovic A, Li H, Sorrentino V, Kutalik Z, Auwerx J, Robinson-Rechavi M. Komljenovic A, et al. Among authors: li h. PLoS Comput Biol. 2019 Jul 3;15(7):e1007162. doi: 10.1371/journal.pcbi.1007162. eCollection 2019 Jul. PLoS Comput Biol. 2019. PMID: 31269015 Free PMC article.

9

The Slc25a47 locus is a novel determinant of hepatic mitochondrial function implicated in liver fibrosis.

Bresciani N, Demagny H, Lemos V, Pontanari F, Li X, Sun Y, Li H, Perino A, Auwerx J, Schoonjans K. Bresciani N, et al. Among authors: li x, li h. J Hepatol. 2022 Oct;77(4):1071-1082. doi: 10.1016/j.jhep.2022.05.040. Epub 2022 Jun 15. J Hepatol. 2022. PMID: 35714811 Free article.

10

Identifying gene function and module connections by the integration of multispecies expression compendia.

Li H, Rukina D, David FPA, Li TY, Oh CM, Gao AW, Katsyuba E, Bou Sleiman M, Komljenovic A, Huang Q, Williams RW, Robinson-Rechavi M, Schoonjans K, Morgenthaler S, Auwerx J. Li H, et al. Among authors: li ty. Genome Res. 2019 Dec;29(12):2034-2045. doi: 10.1101/gr.251983.119. Epub 2019 Nov 21. Genome Res. 2019. PMID: 31754022 Free PMC article.

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