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Algorithm for optimized mRNA design improves stability and immunogenicity.
Zhang H, Zhang L, Lin A, Xu C, Li Z, Liu K, Liu B, Ma X, Zhao F, Jiang H, Chen C, Shen H, Li H, Mathews DH, Zhang Y, Huang L. Zhang H, et al. Among authors: li z, li h. Nature. 2023 Sep;621(7978):396-403. doi: 10.1038/s41586-023-06127-z. Epub 2023 May 2. Nature. 2023. PMID: 37130545 Free PMC article.
A core-shell structured COVID-19 mRNA vaccine with favorable biodistribution pattern and promising immunity.
Yang R, Deng Y, Huang B, Huang L, Lin A, Li Y, Wang W, Liu J, Lu S, Zhan Z, Wang Y, A R, Wang W, Niu P, Zhao L, Li S, Ma X, Zhang L, Zhang Y, Yao W, Liang X, Zhao J, Liu Z, Peng X, Li H, Tan W. Yang R, et al. Among authors: li s, li y, li h. Signal Transduct Target Ther. 2021 May 31;6(1):213. doi: 10.1038/s41392-021-00634-z. Signal Transduct Target Ther. 2021. PMID: 34059617 Free PMC article.
Immunological evaluation of an mRNA vaccine booster in individuals fully immunized with an inactivated SARS-CoV-2 vaccine.
Xu X, Liao Y, Jiang G, Yao W, Duan S, Xiao K, Ding X, Zhao H, Zhang Y, Zhang A, Yang J, Che Y, Zhang J, Zhao F, Ma X, Zhao Z, Cui P, Yang X, Lin X, Cai W, Yan J, Yang Z, Qiu H, Zhang J, Huang L, Shen M, Zhao G, Yu L, Li D, Fan S, Zhang Y, Wang L, He L, Dong F, Xu W, Li H, Li Q. Xu X, et al. Among authors: li d, li h, li q. Clin Transl Med. 2022 Jun;12(6):e875. doi: 10.1002/ctm2.875. Clin Transl Med. 2022. PMID: 35678117 Free PMC article. No abstract available.
Safety and immunogenicity of a modified COVID-19 mRNA vaccine, SW-BIC-213, as a heterologous booster in healthy adults: an open-labeled, two-centered and multi-arm randomised, phase 1 trial.
Gui YZ, Li XN, Li JX, Shen MY, Zhang MW, Cao Y, Xu HR, Li H, Cheng J, Pan L, Yi YL, Liang LY, Yu CY, Liu GY, Yu C, Hu BJ, Zhu FC, Liang F, Shen H, Jia JY, Li HW, Zhou J, Fan J. Gui YZ, et al. Among authors: li hw, li jx, li h, li xn. EBioMedicine. 2023 May;91:104586. doi: 10.1016/j.ebiom.2023.104586. Epub 2023 Apr 24. EBioMedicine. 2023. PMID: 37099843 Free PMC article. Clinical Trial.
Safety, immunogenicity, and efficacy of a modified COVID-19 mRNA vaccine, SW-BIC-213, in healthy people aged 18 years and above: a phase 3 double-blinded, randomized, parallel controlled clinical trial in Lao PDR (Laos).
Fang Y, Li JX, Duangdany D, Li Y, Guo XL, Phamisith C, Yu B, Shen MY, Luo B, Wang YZ, Liu SJ, Zhao FF, Xu CC, Qiu XH, Yan R, Gui YZ, Pei RJ, Wang J, Shen H, Guan WX, Li HW, Mayxay M. Fang Y, et al. Among authors: li hw, li jx, li y. EClinicalMedicine. 2023 Dec 13;67:102372. doi: 10.1016/j.eclinm.2023.102372. eCollection 2024 Jan. EClinicalMedicine. 2023. PMID: 38169790 Free PMC article.
Advances in Development of mRNA-Based Therapeutics.
Huang L, Zhang L, Li W, Li S, Wen J, Li H, Liu Z. Huang L, et al. Among authors: li s, li w, li h. Curr Top Microbiol Immunol. 2022;440:147-166. doi: 10.1007/82_2020_222. Curr Top Microbiol Immunol. 2022. PMID: 32683507
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