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Culture media composition influences patient-derived organoid ability to predict therapeutic responses in gastrointestinal cancers.
Hogenson TL, Xie H, Phillips WJ, Toruner MD, Li JJ, Horn IP, Kennedy DJ, Almada LL, Marks DL, Carr RM, Toruner M, Sigafoos AN, Koenig-Kappes AN, Olson RL, Tolosa EJ, Zhang C, Li H, Doles JD, Bleeker J, Barrett MT, Boyum JH, Kipp BR, Mahipal A, Hubbard JM, Scheffler Hanson TJ, Petersen GM, Dasari S, Oberg AL, Truty MJ, Graham RP, Levy MJ, Zhu M, Billadeau DD, Adjei AA, Dusetti N, Iovanna JL, Bekaii-Saab TS, Ma WW, Fernandez-Zapico ME. Hogenson TL, et al. Among authors: li jj, li h. JCI Insight. 2022 Nov 22;7(22):e158060. doi: 10.1172/jci.insight.158060. JCI Insight. 2022. PMID: 36256477 Free PMC article.
ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and promotes melanoma metastasis through AXL.
Pietrobono S, Anichini G, Sala C, Manetti F, Almada LL, Pepe S, Carr RM, Paradise BD, Sarkaria JN, Davila JI, Tofani L, Battisti I, Arrigoni G, Ying L, Zhang C, Li H, Meves A, Fernandez-Zapico ME, Stecca B. Pietrobono S, et al. Among authors: li h. Nat Commun. 2020 Nov 17;11(1):5865. doi: 10.1038/s41467-020-19575-2. Nat Commun. 2020. PMID: 33203881 Free PMC article.
A rare germline CDKN2A variant (47T>G; p16-L16R) predisposes carriers to pancreatic cancer by reducing cell cycle inhibition.
Horn IP, Marks DL, Koenig AN, Hogenson TL, Almada LL, Goldstein LE, Romecin Duran PA, Vera R, Vrabel AM, Cui G, Rabe KG, Bamlet WR, Mer G, Sicotte H, Zhang C, Li H, Petersen GM, Fernandez-Zapico ME. Horn IP, et al. Among authors: li h. J Biol Chem. 2021 Jan-Jun;296:100634. doi: 10.1016/j.jbc.2021.100634. Epub 2021 Apr 3. J Biol Chem. 2021. PMID: 33823155 Free PMC article.
Nuclear GSK-3β and Oncogenic KRas Lead to the Retention of Pancreatic Ductal Progenitor Cells Phenotypically Similar to Those Seen in IPMN.
Ding L, Roeck K, Zhang C, Zidek B, Rodman E, Hernandez-Barco Y, Zhang JS, Bamlet W, Oberg A, Zhang L, Bardeesy N, Li H, Billadeau D. Ding L, et al. Among authors: li h. Front Cell Dev Biol. 2022 May 13;10:853003. doi: 10.3389/fcell.2022.853003. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35646902 Free PMC article.
112,529 results
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