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Effect of brexanolone on depressive symptoms, anxiety, and insomnia in women with postpartum depression: Pooled analyses from 3 double-blind, randomized, placebo-controlled clinical trials in the HUMMINGBIRD clinical program.
Epperson CN, Rubinow DR, Meltzer-Brody S, Deligiannidis KM, Riesenberg R, Krystal AD, Bankole K, Huang MY, Li H, Brown C, Kanes SJ, Lasser R. Epperson CN, et al. Among authors: li h. J Affect Disord. 2023 Jan 1;320:353-359. doi: 10.1016/j.jad.2022.09.143. Epub 2022 Sep 30. J Affect Disord. 2023. PMID: 36191643 Free article. Clinical Trial.
Brexanolone injection in post-partum depression: two multicentre, double-blind, randomised, placebo-controlled, phase 3 trials.
Meltzer-Brody S, Colquhoun H, Riesenberg R, Epperson CN, Deligiannidis KM, Rubinow DR, Li H, Sankoh AJ, Clemson C, Schacterle A, Jonas J, Kanes S. Meltzer-Brody S, et al. Among authors: li h. Lancet. 2018 Sep 22;392(10152):1058-1070. doi: 10.1016/S0140-6736(18)31551-4. Epub 2018 Aug 31. Lancet. 2018. PMID: 30177236 Clinical Trial.
Patient-reported health-related quality of life from a randomized, placebo-controlled phase 2 trial of zuranolone in adults with major depressive disorder.
Suthoff E, Kosinski M, Arnaud A, Hodgkins P, Gunduz-Bruce H, Lasser R, Silber C, Sankoh AJ, Li H, Werneburg B, Jonas J, Doherty J, Kanes SJ, Bonthapally V. Suthoff E, et al. Among authors: li h. J Affect Disord. 2022 Jul 1;308:19-26. doi: 10.1016/j.jad.2022.03.068. Epub 2022 Apr 2. J Affect Disord. 2022. PMID: 35378149 Free article. Clinical Trial.
Trial of SAGE-217 in Patients with Major Depressive Disorder.
Gunduz-Bruce H, Silber C, Kaul I, Rothschild AJ, Riesenberg R, Sankoh AJ, Li H, Lasser R, Zorumski CF, Rubinow DR, Paul SM, Jonas J, Doherty JJ, Kanes SJ. Gunduz-Bruce H, et al. Among authors: li h. N Engl J Med. 2019 Sep 5;381(10):903-911. doi: 10.1056/NEJMoa1815981. N Engl J Med. 2019. PMID: 31483961 Clinical Trial.
Allopregnanolone Concentrations in Breast Milk and Plasma from Healthy Volunteers Receiving Brexanolone Injection, With Population Pharmacokinetic Modeling of Potential Relative Infant Dose.
Wald J, Henningsson A, Hanze E, Hoffmann E, Li H, Colquhoun H, Deligiannidis KM. Wald J, et al. Among authors: li h. Clin Pharmacokinet. 2022 Sep;61(9):1307-1319. doi: 10.1007/s40262-022-01155-w. Epub 2022 Jul 23. Clin Pharmacokinet. 2022. PMID: 35869362 Free PMC article. Clinical Trial.
Use of composite endpoints in clinical trials.
Sankoh AJ, Li H, D'Agostino RB Sr. Sankoh AJ, et al. Among authors: li h. Stat Med. 2016 Jan 30;35(2):319-20. doi: 10.1002/sim.6581. Stat Med. 2016. PMID: 26767752 No abstract available.
Use of composite endpoints in clinical trials.
Sankoh AJ, Li H, D'Agostino RB Sr. Sankoh AJ, et al. Among authors: li h. Stat Med. 2014 Nov 30;33(27):4709-14. doi: 10.1002/sim.6205. Epub 2014 May 15. Stat Med. 2014. PMID: 24833282
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