Li H - Search Results

1

Synthesis of bis-macrocyclic HCV protease inhibitor MK-6325 via intramolecular sp²-sp³ Suzuki-Miyaura coupling and ring closing metathesis.

Li H, Scott JP, Chen CY, Journet M, Belyk K, Balsells J, Kosjek B, Baxter CA, Stewart GW, Wise C, Alam M, Song ZJ, Tan L. Li H, et al. Org Lett. 2015 Mar 20;17(6):1533-6. doi: 10.1021/acs.orglett.5b00418. Epub 2015 Mar 10. Org Lett. 2015. PMID: 25754231

2

A Concise and Atom-Economical Suzuki-Miyaura Coupling Reaction Using Unactivated Trialkyl- and Triarylboranes with Aryl Halides.

Li H, Zhong YL, Chen CY, Ferraro AE, Wang D. Li H, et al. Org Lett. 2015 Jul 17;17(14):3616-9. doi: 10.1021/acs.orglett.5b01720. Epub 2015 Jun 30. Org Lett. 2015. PMID: 26125106

3

A divergent and selective synthesis of isomeric benzoxazoles from a single N-Cl imine.

Chen CY, Andreani T, Li H. Chen CY, et al. Among authors: li h. Org Lett. 2011 Dec 2;13(23):6300-3. doi: 10.1021/ol202844c. Epub 2011 Nov 8. Org Lett. 2011. PMID: 22067007

4

Synthesis of the HCV protease inhibitor Vaniprevir (MK-7009) using ring-closing metathesis strategy.

Kong J, Chen CY, Balsells-Padros J, Cao Y, Dunn RF, Dolman SJ, Janey J, Li H, Zacuto MJ. Kong J, et al. Among authors: li h. J Org Chem. 2012 Apr 20;77(8):3820-8. doi: 10.1021/jo3001595. Epub 2012 Apr 10. J Org Chem. 2012. PMID: 22458448

5

Enantioselective synthesis of an HCV NS5a antagonist.

Mangion IK, Chen CY, Li H, Maligres P, Chen Y, Christensen M, Cohen R, Jeon I, Klapars A, Krska S, Nguyen H, Reamer RA, Sherry BD, Zavialov I. Mangion IK, et al. Among authors: li h. Org Lett. 2014 May 2;16(9):2310-3. doi: 10.1021/ol500971c. Epub 2014 Apr 11. Org Lett. 2014. PMID: 24724971

6

Asymmetric synthesis of cyclic indole aminals via 1,3-stereoinduction.

Li H, Chen CY, Nguyen H, Cohen R, Maligres PE, Yasuda N, Mangion I, Zavialov I, Reibarkh M, Chung JY. Li H, et al. J Org Chem. 2014 Sep 19;79(18):8533-40. doi: 10.1021/jo501581e. Epub 2014 Sep 3. J Org Chem. 2014. PMID: 25162915

7

Suzuki-Miyaura cross-coupling reactions of unprotected haloimidazoles.

Tan J, Chen Y, Li H, Yasuda N. Tan J, et al. Among authors: li h. J Org Chem. 2014 Sep 19;79(18):8871-6. doi: 10.1021/jo501326r. Epub 2014 Aug 27. J Org Chem. 2014. PMID: 25140886

8

Tricyclic sulfones as orally active gamma-secretase inhibitors: synthesis and structure-activity relationship studies.

Sasikumar TK, Qiang L, Burnett DA, Cole D, Xu R, Li H, Greenlee WJ, Clader J, Zhang L, Hyde L. Sasikumar TK, et al. Among authors: li h. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3632-5. doi: 10.1016/j.bmcl.2010.04.104. Epub 2010 May 5. Bioorg Med Chem Lett. 2010. PMID: 20493690

9

Regioselective synthesis of the bridged tricyclic core of Garcinia natural products via intramolecular aryl acrylate cycloadditions.

Tisdale EJ, Chowdhury C, Vong BG, Li H, Theodorakis EA. Tisdale EJ, et al. Among authors: li h. Org Lett. 2002 Mar 21;4(6):909-12. doi: 10.1021/ol017278w. Org Lett. 2002. PMID: 11893183

10

Design and synthesis of tricyclic sulfones as gamma-secretase inhibitors with greatly reduced Notch toxicity.

Xu R, Cole D, Asberom T, Bara T, Bennett C, Burnett DA, Clader J, Domalski M, Greenlee W, Hyde L, Josien H, Li H, McBriar M, McKittrick B, McPhail AT, Pissarnitski D, Qiang L, Rajagopalan M, Sasikumar T, Su J, Tang H, Wu WL, Zhang L, Zhao Z. Xu R, et al. Among authors: li h. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2591-6. doi: 10.1016/j.bmcl.2010.02.080. Epub 2010 Feb 23. Bioorg Med Chem Lett. 2010. PMID: 20236824

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