Li CC - Search Results

1

Target Fishing Reveals a Novel Mechanism of 1,2,4-Oxadiazole Derivatives Targeting Rpn6, a Subunit of 26S Proteasome.

Dai Z, An LY, Chen XY, Yang F, Zhao N, Li CC, Ren R, Li BY, Tao WY, Li P, Jiang C, Yan F, Jiang ZY, You QD, Di B, Xu LL. Dai Z, et al. Among authors: li cc, li by, li p. J Med Chem. 2022 Mar 24;65(6):5029-5043. doi: 10.1021/acs.jmedchem.1c02210. Epub 2022 Mar 6. J Med Chem. 2022. PMID: 35253427

2

Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 3: optimization of [1,2,4]triazolo[1,5-a]pyrimidine core via structure-based and physicochemical property-driven approaches.

Huang B, Li C, Chen W, Liu T, Yu M, Fu L, Sun Y, Liu H, De Clercq E, Pannecouque C, Balzarini J, Zhan P, Liu X. Huang B, et al. Eur J Med Chem. 2015 Mar 6;92:754-65. doi: 10.1016/j.ejmech.2015.01.042. Epub 2015 Jan 22. Eur J Med Chem. 2015. PMID: 25626145

3

3-(1H-Benzo[d]imidazol-6-yl)-5-(4-fluorophenyl)-1,2,4-oxadiazole (DDO7232), a Novel Potent Nrf2/ARE Inducer, Ameliorates DSS-Induced Murine Colitis and Protects NCM460 Cells against Oxidative Stress via ERK1/2 Phosphorylation.

Xu LL, Liu T, Wang L, Li L, Wu YF, Li CC, Di B, You QD, Jiang ZY. Xu LL, et al. Among authors: li cc, li l. Oxid Med Cell Longev. 2018 May 20;2018:3271617. doi: 10.1155/2018/3271617. eCollection 2018. Oxid Med Cell Longev. 2018. PMID: 29887940 Free PMC article.

4

Structure-activity and structure-property relationships of novel Nrf2 activators with a 1,2,4-oxadiazole core and their therapeutic effects on acetaminophen (APAP)-induced acute liver injury.

Xu LL, Wu YF, Wang L, Li CC, Li L, Di B, You QD, Jiang ZY. Xu LL, et al. Among authors: li cc, li l. Eur J Med Chem. 2018 Sep 5;157:1376-1394. doi: 10.1016/j.ejmech.2018.08.071. Epub 2018 Aug 28. Eur J Med Chem. 2018. PMID: 30196061

5

Corrigendum to "3-(1H-Benzo[d]imidazol-6-yl)-5-(4-fluorophenyl)-1, 2, 4-oxadiazole (DDO7232), a Novel Potent Nrf2/ARE Inducer, Ameliorates DSS-Induced Murine Colitis and Protects NCM460 Cells against Oxidative Stress via ERK1/2 Phosphorylation".

Xu LL, Liu T, Wang L, Li L, Wu YF, Li CC, Di B, You QD, Jiang ZY. Xu LL, et al. Among authors: li cc, li l. Oxid Med Cell Longev. 2018 Oct 29;2018:8780453. doi: 10.1155/2018/8780453. eCollection 2018. Oxid Med Cell Longev. 2018. PMID: 30510629 Free PMC article.

6

5-(3,4-Difluorophenyl)-3-(6-methylpyridin-3-yl)-1,2,4-oxadiazole (DDO-7263), a novel Nrf2 activator targeting brain tissue, protects against MPTP-induced subacute Parkinson's disease in mice by inhibiting the NLRP3 inflammasome and protects PC12 cells against oxidative stress.

Xu LL, Wu YF, Yan F, Li CC, Dai Z, You QD, Jiang ZY, Di B. Xu LL, et al. Among authors: li cc. Free Radic Biol Med. 2019 Apr;134:288-303. doi: 10.1016/j.freeradbiomed.2019.01.003. Epub 2019 Jan 5. Free Radic Biol Med. 2019. PMID: 30615919

7

Selective apoptosis-inducing activity of synthetic hydrocarbon-stapled SOS1 helix with d-amino acids in H358 cancer cells expressing KRAS^G12C.

Xu LL, Li CC, An LY, Dai Z, Chen XY, You QD, Hu C, Di B. Xu LL, et al. Among authors: li cc. Eur J Med Chem. 2020 Jan 1;185:111844. doi: 10.1016/j.ejmech.2019.111844. Epub 2019 Nov 2. Eur J Med Chem. 2020. PMID: 31706640

8

Recent advances in the NEK7-licensed NLRP3 inflammasome activation: Mechanisms, role in diseases and related inhibitors.

Zhao N, Li CC, Di B, Xu LL. Zhao N, et al. Among authors: li cc. J Autoimmun. 2020 Sep;113:102515. doi: 10.1016/j.jaut.2020.102515. Epub 2020 Jul 20. J Autoimmun. 2020. PMID: 32703754 Review.

9

Development of Novel Tetrahydroquinoline Inhibitors of NLRP3 Inflammasome for Potential Treatment of DSS-Induced Mouse Colitis.

Dai Z, Chen XY, An LY, Li CC, Zhao N, Yang F, You ST, Hou CZ, Li K, Jiang C, You QD, Di B, Xu LL. Dai Z, et al. Among authors: li cc, li k. J Med Chem. 2021 Jan 14;64(1):871-889. doi: 10.1021/acs.jmedchem.0c01924. Epub 2020 Dec 17. J Med Chem. 2021. PMID: 33332136

10

Apoptosis-inducing activity of synthetic hydrocarbon-stapled peptides in H358 cancer cells expressing KRAS^G12C.

Li C, Zhao N, An L, Dai Z, Chen X, Yang F, You Q, Di B, Hu C, Xu L. Li C, et al. Acta Pharm Sin B. 2021 Sep;11(9):2670-2684. doi: 10.1016/j.apsb.2021.06.013. Epub 2021 Jun 25. Acta Pharm Sin B. 2021. PMID: 34589388 Free PMC article.

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