Li C - Search Results

1

Cas9-mediated replacement of expanded CAG repeats in a pig model of Huntington's disease.

Yan S, Zheng X, Lin Y, Li C, Liu Z, Li J, Tu Z, Zhao Y, Huang C, Chen Y, Li J, Song X, Han B, Wang W, Liang W, Lai L, Li XJ, Li S. Yan S, et al. Among authors: li c, li s, li j, li xj. Nat Biomed Eng. 2023 May;7(5):629-646. doi: 10.1038/s41551-023-01007-3. Epub 2023 Feb 16. Nat Biomed Eng. 2023. PMID: 36797418

2

CRISPR/Cas9-mediated disruption of SHANK3 in monkey leads to drug-treatable autism-like symptoms.

Tu Z, Zhao H, Li B, Yan S, Wang L, Tang Y, Li Z, Bai D, Li C, Lin Y, Li Y, Liu J, Xu H, Guo X, Jiang YH, Zhang YQ, Li XJ. Tu Z, et al. Among authors: li c, li y, li z, li xj, li b. Hum Mol Genet. 2019 Feb 15;28(4):561-571. doi: 10.1093/hmg/ddy367. Hum Mol Genet. 2019. PMID: 30329048 Free PMC article.

3

Differential development and electrophysiological activity in cultured cortical neurons from the mouse and cynomolgus monkey.

Zhang XY, Li J, Li CJ, Lin YQ, Huang CH, Zheng X, Song XC, Tu ZC, Li XJ, Yan S. Zhang XY, et al. Neural Regen Res. 2021 Dec;16(12):2446-2452. doi: 10.4103/1673-5374.313056. Neural Regen Res. 2021. PMID: 33907033 Free PMC article.

4

TBN improves motor function and prolongs survival in a TDP-43M337V mouse model of ALS.

Huang C, Li J, Zhang G, Lin Y, Li C, Zheng X, Song X, Han B, Guo B, Tu Z, Zhang J, Sun Y, Wang Y, Zhang Z, Yan S. Huang C, et al. Among authors: li c, li j. Hum Mol Genet. 2021 Jul 28;30(16):1484-1496. doi: 10.1093/hmg/ddab101. Hum Mol Genet. 2021. PMID: 33929499

5

Application of CRISPR/Cas9 System in Establishing Large Animal Models.

Lin Y, Li J, Li C, Tu Z, Li S, Li XJ, Yan S. Lin Y, et al. Among authors: li c, li s, li j, li xj. Front Cell Dev Biol. 2022 May 17;10:919155. doi: 10.3389/fcell.2022.919155. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35656550 Free PMC article. Review.

6

Intravenous AAV9 administration results in safe and widespread distribution of transgene in the brain of mini-pig.

Lin Y, Li C, Wang W, Li J, Huang C, Zheng X, Liu Z, Song X, Chen Y, Gao J, Wu J, Wu J, Tu Z, Lai L, Li XJ, Li S, Yan S. Lin Y, et al. Among authors: li c, li s, li j, li xj. Front Cell Dev Biol. 2023 Jan 24;10:1115348. doi: 10.3389/fcell.2022.1115348. eCollection 2022. Front Cell Dev Biol. 2023. PMID: 36762127 Free PMC article.

7

Generation of inactivated IL2RG and RAG1 monkeys with severe combined immunodeficiency using base editing.

Zheng X, Huang C, Lin Y, Han B, Chen Y, Li C, Li J, Ding Y, Song X, Wang W, Liang W, Wu J, Wu J, Gao J, Wei C, Zhang X, Tu Z, Yan S. Zheng X, et al. Among authors: li c, li j. Signal Transduct Target Ther. 2023 Sep 4;8(1):327. doi: 10.1038/s41392-023-01544-y. Signal Transduct Target Ther. 2023. PMID: 37661226 Free PMC article.

8

A Specific Mini-Intrabody Mediates Lysosome Degradation of Mutant Huntingtin.

Li C, Lin Y, Chen Y, Song X, Zheng X, Li J, He J, Chen X, Huang C, Wang W, Wu J, Wu J, Gao J, Tu Z, Li XJ, Yan S, Li S. Li C, et al. Among authors: li s, li j, li xj. Adv Sci (Weinh). 2023 Nov;10(31):e2301120. doi: 10.1002/advs.202301120. Epub 2023 Sep 8. Adv Sci (Weinh). 2023. PMID: 37688357 Free PMC article.

9

Aberrant splicing of mutant huntingtin in Huntington's disease knock-in pigs.

Tong H, Yang T, Liu L, Li C, Sun Y, Jia Q, Qin Y, Chen L, Zhao X, Zhou G, Yan S, Li XJ, Li S. Tong H, et al. Among authors: li c, li s, li xj. Neurobiol Dis. 2023 Oct 15;187:106291. doi: 10.1016/j.nbd.2023.106291. Epub 2023 Sep 15. Neurobiol Dis. 2023. PMID: 37716514 Free article.

10

Tauopathy promotes spinal cord-dependent production of toxic amyloid-beta in transgenic monkeys.

Tu Z, Yan S, Han B, Li C, Liang W, Lin Y, Ding Y, Wei H, Wang L, Xu H, Ye J, Li B, Li S, Li XJ. Tu Z, et al. Among authors: li c, li s, li xj, li b. Signal Transduct Target Ther. 2023 Sep 22;8(1):358. doi: 10.1038/s41392-023-01601-6. Signal Transduct Target Ther. 2023. PMID: 37735155 Free PMC article.

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