Leyssen P - Search Results

1

Novel 1,2,4-triazole and imidazole derivatives of L-ascorbic and imino-ascorbic acid: synthesis, anti-HCV and antitumor activity evaluations.

Wittine K, Stipković Babić M, Makuc D, Plavec J, Kraljević Pavelić S, Sedić M, Pavelić K, Leyssen P, Neyts J, Balzarini J, Mintas M. Wittine K, et al. Among authors: leyssen p. Bioorg Med Chem. 2012 Jun 1;20(11):3675-85. doi: 10.1016/j.bmc.2012.01.054. Epub 2012 Feb 15. Bioorg Med Chem. 2012. PMID: 22555152

2

Perspectives for the treatment of infections with Flaviviridae.

Leyssen P, De Clercq E, Neyts J. Leyssen P, et al. Clin Microbiol Rev. 2000 Jan;13(1):67-82, table of contents. doi: 10.1128/CMR.13.1.67. Clin Microbiol Rev. 2000. PMID: 10627492 Free PMC article. Review.

3

Acyclic/carbocyclic guanosine analogues as anti-herpesvirus agents.

De Clercq E, Andrei G, Snoeck R, De Bolle L, Naesens L, Degrève B, Balzarini J, Zhang Y, Schols D, Leyssen P, Ying C, Neyts J. De Clercq E, et al. Among authors: leyssen p. Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):271-85. doi: 10.1081/NCN-100002298. Nucleosides Nucleotides Nucleic Acids. 2001. PMID: 11563039 Review.

4

Efficacy of cidofovir in a murine model of disseminated progressive vaccinia.

Neyts J, Leyssen P, Verbeken E, De Clercq E. Neyts J, et al. Among authors: leyssen p. Antimicrob Agents Chemother. 2004 Jun;48(6):2267-73. doi: 10.1128/AAC.48.6.2267-2273.2004. Antimicrob Agents Chemother. 2004. PMID: 15155231 Free PMC article.

5

Rodent models for the study of therapy against flavivirus infections.

Charlier N, Leyssen P, De Clercq E, Neyts J. Charlier N, et al. Among authors: leyssen p. Antiviral Res. 2004 Aug;63(2):67-77. doi: 10.1016/j.antiviral.2004.06.007. Antiviral Res. 2004. PMID: 15321702 Review.

6

The predominant mechanism by which ribavirin exerts its antiviral activity in vitro against flaviviruses and paramyxoviruses is mediated by inhibition of IMP dehydrogenase.

Leyssen P, Balzarini J, De Clercq E, Neyts J. Leyssen P, et al. J Virol. 2005 Feb;79(3):1943-7. doi: 10.1128/JVI.79.3.1943-1947.2005. J Virol. 2005. PMID: 15650220 Free PMC article.

7

Antiviral potential of a new generation of acyclic nucleoside phosphonates, the 6-[2-(phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines.

De Clercq E, Andrei G, Balzarini J, Leyssen P, Naesens L, Neyts J, Pannecouque C, Snoeck R, Ying C, Hocková D, Holý A. De Clercq E, et al. Among authors: leyssen p. Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):331-41. doi: 10.1081/ncn-200059772. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16247948

8

The anti-yellow fever virus activity of ribavirin is independent of error-prone replication.

Leyssen P, De Clercq E, Neyts J. Leyssen P, et al. Mol Pharmacol. 2006 Apr;69(4):1461-7. doi: 10.1124/mol.105.020057. Epub 2006 Jan 18. Mol Pharmacol. 2006. PMID: 16421290

9

Molecular strategies to inhibit the replication of RNA viruses.

Leyssen P, De Clercq E, Neyts J. Leyssen P, et al. Antiviral Res. 2008 Apr;78(1):9-25. doi: 10.1016/j.antiviral.2008.01.004. Epub 2008 Feb 4. Antiviral Res. 2008. PMID: 18313769 Free PMC article. Review.

10

Comparative in vitro anti-hepatitis C virus activities of a selected series of polymerase, protease, and helicase inhibitors.

Paeshuyse J, Vliegen I, Coelmont L, Leyssen P, Tabarrini O, Herdewijn P, Mittendorfer H, Easmon J, Cecchetti V, Bartenschlager R, Puerstinger G, Neyts J. Paeshuyse J, et al. Among authors: leyssen p. Antimicrob Agents Chemother. 2008 Sep;52(9):3433-7. doi: 10.1128/AAC.01534-07. Epub 2008 Jul 14. Antimicrob Agents Chemother. 2008. PMID: 18625766 Free PMC article.

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