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Page 1
GnRH replacement rescues cognition in Down syndrome.
Manfredi-Lozano M, Leysen V, Adamo M, Paiva I, Rovera R, Pignat JM, Timzoura FE, Candlish M, Eddarkaoui S, Malone SA, Silva MSB, Trova S, Imbernon M, Decoster L, Cotellessa L, Tena-Sempere M, Claret M, Paoloni-Giacobino A, Plassard D, Paccou E, Vionnet N, Acierno J, Maceski AM, Lutti A, Pfrieger F, Rasika S, Santoni F, Boehm U, Ciofi P, Buée L, Haddjeri N, Boutillier AL, Kuhle J, Messina A, Draganski B, Giacobini P, Pitteloud N, Prevot V. Manfredi-Lozano M, et al. Among authors: leysen v. Science. 2022 Sep 2;377(6610):eabq4515. doi: 10.1126/science.abq4515. Epub 2022 Sep 2. Science. 2022. PMID: 36048943 Free PMC article.
NOS1 mutations cause hypogonadotropic hypogonadism with sensory and cognitive deficits that can be reversed in infantile mice.
Chachlaki K, Messina A, Delli V, Leysen V, Maurnyi C, Huber C, Ternier G, Skrapits K, Papadakis G, Shruti S, Kapanidou M, Cheng X, Acierno J, Rademaker J, Rasika S, Quinton R, Niedziela M, L'Allemand D, Pignatelli D, Dirlewander M, Lang-Muritano M, Kempf P, Catteau-Jonard S, Niederländer NJ, Ciofi P, Tena-Sempere M, Garthwaite J, Storme L, Avan P, Hrabovszky E, Carleton A, Santoni F, Giacobini P, Pitteloud N, Prevot V. Chachlaki K, et al. Among authors: leysen v. Sci Transl Med. 2022 Oct 5;14(665):eabh2369. doi: 10.1126/scitranslmed.abh2369. Epub 2022 Oct 5. Sci Transl Med. 2022. PMID: 36197968 Free PMC article.
Image-guided phenotyping of ovariectomized mice: altered functional connectivity, cognition, myelination, and dopaminergic functionality.
Anckaerts C, van Gastel J, Leysen V, Hinz R, Azmi A, Simoens P, Shah D, Kara F, Langbeen A, Bols P, Laloux C, Prevot V, Verhoye M, Maudsley S, Van der Linden A. Anckaerts C, et al. Among authors: leysen v. Neurobiol Aging. 2019 Feb;74:77-89. doi: 10.1016/j.neurobiolaging.2018.10.012. Epub 2018 Oct 17. Neurobiol Aging. 2019. PMID: 30439596
Long-term ovarian hormone deprivation alters functional connectivity, brain neurochemical profile and white matter integrity in the Tg2576 amyloid mouse model of Alzheimer's disease.
Kara F, Belloy ME, Voncken R, Sarwari Z, Garima Y, Anckaerts C, Langbeen A, Leysen V, Shah D, Jacobs J, Hamaide J, Bols P, Van Audekerke J, Daans J, Guglielmetti C, Kantarci K, Prevot V, Roßner S, Ponsaerts P, Van der Linden A, Verhoye M. Kara F, et al. Among authors: leysen v. Neurobiol Aging. 2021 Jun;102:139-150. doi: 10.1016/j.neurobiolaging.2021.02.011. Epub 2021 Feb 22. Neurobiol Aging. 2021. PMID: 33765427 Free PMC article.
Oral perception in tongue thrust and other oral habits.
Dahan JS, Lelong O, Celant S, Leysen V. Dahan JS, et al. Among authors: leysen v. Am J Orthod Dentofacial Orthop. 2000 Oct;118(4):385-91. doi: 10.1067/mod.2000.109101. Am J Orthod Dentofacial Orthop. 2000. PMID: 11029733