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SORL1 mutation in a Greek family with Parkinson's disease and dementia.
Xiromerisiou G, Bourinaris T, Houlden H, Lewis PA, Senkevich K, Hammer M, Federoff M, Khan A, Spanaki C, Hadjigeorgiou GM, Bonstanjopoulou S, Fidani L, Ermolaev A, Gan-Or Z, Singleton A, Vandrovcova J, Hardy J. Xiromerisiou G, et al. Among authors: lewis pa. Ann Clin Transl Neurol. 2021 Oct;8(10):1961-1969. doi: 10.1002/acn3.51433. Epub 2021 Sep 10. Ann Clin Transl Neurol. 2021. PMID: 34506082 Free PMC article.
Variant Alzheimer's disease with spastic paraparesis and cotton wool plaques is caused by PS-1 mutations that lead to exceptionally high amyloid-beta concentrations.
Houlden H, Baker M, McGowan E, Lewis P, Hutton M, Crook R, Wood NW, Kumar-Singh S, Geddes J, Swash M, Scaravilli F, Holton JL, Lashley T, Tomita T, Hashimoto T, Verkkoniemi A, Kalimo H, Somer M, Paetau A, Martin JJ, Van Broeckhoven C, Golde T, Hardy J, Haltia M, Revesz T. Houlden H, et al. Ann Neurol. 2000 Nov;48(5):806-8. Ann Neurol. 2000. PMID: 11079548
Genetic neuropathology of Parkinson's disease.
Cookson MR, Hardy J, Lewis PA. Cookson MR, et al. Among authors: lewis pa. Int J Clin Exp Pathol. 2008 Jan 1;1(3):217-31. Int J Clin Exp Pathol. 2008. PMID: 18784814 Free PMC article.
Creation of an open-access, mutation-defined fibroblast resource for neurological disease research.
Wray S, Self M; NINDS Parkinson's Disease iPSC Consortium; NINDS Huntington's Disease iPSC Consortium; NINDS ALS iPSC Consortium; Lewis PA, Taanman JW, Ryan NS, Mahoney CJ, Liang Y, Devine MJ, Sheerin UM, Houlden H, Morris HR, Healy D, Marti-Masso JF, Preza E, Barker S, Sutherland M, Corriveau RA, D'Andrea M, Schapira AH, Uitti RJ, Guttman M, Opala G, Jasinska-Myga B, Puschmann A, Nilsson C, Espay AJ, Slawek J, Gutmann L, Boeve BF, Boylan K, Stoessl AJ, Ross OA, Maragakis NJ, Van Gerpen J, Gerstenhaber M, Gwinn K, Dawson TM, Isacson O, Marder KS, Clark LN, Przedborski SE, Finkbeiner S, Rothstein JD, Wszolek ZK, Rossor MN, Hardy J. Wray S, et al. Among authors: lewis pa. PLoS One. 2012;7(8):e43099. doi: 10.1371/journal.pone.0043099. Epub 2012 Aug 27. PLoS One. 2012. PMID: 22952635 Free PMC article.
α-Synuclein mutations cluster around a putative protein loop.
Kara E, Lewis PA, Ling H, Proukakis C, Houlden H, Hardy J. Kara E, et al. Among authors: lewis pa. Neurosci Lett. 2013 Jun 24;546:67-70. doi: 10.1016/j.neulet.2013.04.058. Epub 2013 May 10. Neurosci Lett. 2013. PMID: 23669636 Free PMC article.
The Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy.
Burchell VS, Nelson DE, Sanchez-Martinez A, Delgado-Camprubi M, Ivatt RM, Pogson JH, Randle SJ, Wray S, Lewis PA, Houlden H, Abramov AY, Hardy J, Wood NW, Whitworth AJ, Laman H, Plun-Favreau H. Burchell VS, et al. Among authors: lewis pa. Nat Neurosci. 2013 Sep;16(9):1257-65. doi: 10.1038/nn.3489. Epub 2013 Aug 11. Nat Neurosci. 2013. PMID: 23933751 Free PMC article.
LRRK2: cause, risk, and mechanism.
Paisán-Ruiz C, Lewis PA, Singleton AB. Paisán-Ruiz C, et al. Among authors: lewis pa. J Parkinsons Dis. 2013;3(2):85-103. doi: 10.3233/JPD-130192. J Parkinsons Dis. 2013. PMID: 23938341 Free PMC article. Review.
366 results