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A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma.
Lytle NK, Ferguson LP, Rajbhandari N, Gilroy K, Fox RG, Deshpande A, Schürch CM, Hamilton M, Robertson N, Lin W, Noel P, Wartenberg M, Zlobec I, Eichmann M, Galván JA, Karamitopoulou E, Gilderman T, Esparza LA, Shima Y, Spahn P, French R, Lewis NE, Fisch KM, Sasik R, Rosenthal SB, Kritzik M, Von Hoff D, Han H, Ideker T, Deshpande AJ, Lowy AM, Adams PD, Reya T. Lytle NK, et al. Among authors: lewis ne. Cell. 2019 Apr 18;177(3):572-586.e22. doi: 10.1016/j.cell.2019.03.010. Epub 2019 Apr 4. Cell. 2019. PMID: 30955884 Free PMC article.
Systems glycobiology for glycoengineering.
Spahn PN, Lewis NE. Spahn PN, et al. Among authors: lewis ne. Curr Opin Biotechnol. 2014 Dec;30:218-24. doi: 10.1016/j.copbio.2014.08.004. Epub 2014 Sep 7. Curr Opin Biotechnol. 2014. PMID: 25202878 Review.
Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions.
Shen JP, Zhao D, Sasik R, Luebeck J, Birmingham A, Bojorquez-Gomez A, Licon K, Klepper K, Pekin D, Beckett AN, Sanchez KS, Thomas A, Kuo CC, Du D, Roguev A, Lewis NE, Chang AN, Kreisberg JF, Krogan N, Qi L, Ideker T, Mali P. Shen JP, et al. Among authors: lewis ne. Nat Methods. 2017 Jun;14(6):573-576. doi: 10.1038/nmeth.4225. Epub 2017 Mar 20. Nat Methods. 2017. PMID: 28319113 Free PMC article.
ZNF263 is a transcriptional regulator of heparin and heparan sulfate biosynthesis.
Weiss RJ, Spahn PN, Toledo AG, Chiang AWT, Kellman BP, Li J, Benner C, Glass CK, Gordts PLSM, Lewis NE, Esko JD. Weiss RJ, et al. Among authors: lewis ne. Proc Natl Acad Sci U S A. 2020 Apr 28;117(17):9311-9317. doi: 10.1073/pnas.1920880117. Epub 2020 Apr 10. Proc Natl Acad Sci U S A. 2020. PMID: 32277030 Free PMC article.
Genome-wide screens uncover KDM2B as a modifier of protein binding to heparan sulfate.
Weiss RJ, Spahn PN, Chiang AWT, Liu Q, Li J, Hamill KM, Rother S, Clausen TM, Hoeksema MA, Timm BM, Godula K, Glass CK, Tor Y, Gordts PLSM, Lewis NE, Esko JD. Weiss RJ, et al. Among authors: lewis ne. Nat Chem Biol. 2021 Jun;17(6):684-692. doi: 10.1038/s41589-021-00776-9. Epub 2021 Apr 12. Nat Chem Biol. 2021. PMID: 33846619 Free PMC article.
191 results