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Intradermal-delivered DNA vaccine induces durable immunity mediating a reduction in viral load in a rhesus macaque SARS-CoV-2 challenge model.
Patel A, Walters JN, Reuschel EL, Schultheis K, Parzych E, Gary EN, Maricic I, Purwar M, Eblimit Z, Walker SN, Guimet D, Bhojnagarwala P, Adeniji OS, Doan A, Xu Z, Elwood D, Reeder SM, Pessaint L, Kim KY, Cook A, Chokkalingam N, Finneyfrock B, Tello-Ruiz E, Dodson A, Choi J, Generotti A, Harrison J, Tursi NJ, Andrade VM, Dia Y, Zaidi FI, Andersen H, Abdel-Mohsen M, Lewis MG, Muthumani K, Kim JJ, Kulp DW, Humeau LM, Ramos SJ, Smith TRF, Weiner DB, Broderick KE. Patel A, et al. Among authors: lewis mg. Cell Rep Med. 2021 Oct 19;2(10):100420. doi: 10.1016/j.xcrm.2021.100420. Epub 2021 Sep 28. Cell Rep Med. 2021. PMID: 34604818 Free PMC article.
DNA prime Listeria boost induces a cellular immune response to SIV antigens in the rhesus macaque model that is capable of limited suppression of SIV239 viral replication.
Boyer JD, Robinson TM, Maciag PC, Peng X, Johnson RS, Pavlakis G, Lewis MG, Shen A, Siliciano R, Brown CR, Weiner DB, Paterson Y. Boyer JD, et al. Among authors: lewis mg. Virology. 2005 Mar 1;333(1):88-101. doi: 10.1016/j.virol.2004.12.026. Virology. 2005. PMID: 15708595 Free article.
A DNA prime-oral Listeria boost vaccine in rhesus macaques induces a SIV-specific CD8 T cell mucosal response characterized by high levels of alpha4beta7 integrin and an effector memory phenotype.
Neeson P, Boyer J, Kumar S, Lewis MG, Mattias L, Veazey R, Weiner D, Paterson Y. Neeson P, et al. Among authors: lewis mg. Virology. 2006 Oct 25;354(2):299-315. doi: 10.1016/j.virol.2006.06.036. Epub 2006 Aug 9. Virology. 2006. PMID: 16904153 Free PMC article.
399 results