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Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility.
Sazonovs A, Stevens CR, Venkataraman GR, Yuan K, Avila B, Abreu MT, Ahmad T, Allez M, Ananthakrishnan AN, Atzmon G, Baras A, Barrett JC, Barzilai N, Beaugerie L, Beecham A, Bernstein CN, Bitton A, Bokemeyer B, Chan A, Chung D, Cleynen I, Cosnes J, Cutler DJ, Daly A, Damas OM, Datta LW, Dawany N, Devoto M, Dodge S, Ellinghaus E, Fachal L, Farkkila M, Faubion W, Ferreira M, Franchimont D, Gabriel SB, Ge T, Georges M, Gettler K, Giri M, Glaser B, Goerg S, Goyette P, Graham D, Hämäläinen E, Haritunians T, Heap GA, Hiltunen M, Hoeppner M, Horowitz JE, Irving P, Iyer V, Jalas C, Kelsen J, Khalili H, Kirschner BS, Kontula K, Koskela JT, Kugathasan S, Kupcinskas J, Lamb CA, Laudes M, Lévesque C, Levine AP, Lewis JD, Liefferinckx C, Loescher BS, Louis E, Mansfield J, May S, McCauley JL, Mengesha E, Mni M, Moayyedi P, Moran CJ, Newberry RD, O'Charoen S, Okou DT, Oldenburg B, Ostrer H, Palotie A, Paquette J, Pekow J, Peter I, Pierik MJ, Ponsioen CY, Pontikos N, Prescott N, Pulver AE, Rahmouni S, Rice DL, Saavalainen P, Sands B, Sartor RB, Schiff ER, Schreiber S, Schumm LP, Segal AW, Seksik P, Shawky R, Sheikh SZ, Silverberg MS, Simmons A, Skeiceviciene J, Sokol H, Solomonson M, Somine… See abstract for full author list ➔ Sazonovs A, et al. Among authors: lewis jd. Nat Genet. 2022 Sep;54(9):1275-1283. doi: 10.1038/s41588-022-01156-2. Epub 2022 Aug 29. Nat Genet. 2022. PMID: 36038634 Free PMC article.
Design issues and outcomes in IBD clinical trials.
Sands BE, Abreu MT, Ferry GD, Griffiths AM, Hanauer SB, Isaacs KL, Lewis JD, Sandborn WJ, Steinhart AH. Sands BE, et al. Among authors: lewis jd. Inflamm Bowel Dis. 2005 Nov;11 Suppl 1:S22-8. doi: 10.1097/01.mib.0000184849.38816.39. Inflamm Bowel Dis. 2005. PMID: 16254479 Review.
State of the art: IBD therapy and clinical trials in IBD.
Isaacs KL, Lewis JD, Sandborn WJ, Sands BE, Targan SR. Isaacs KL, et al. Among authors: lewis jd. Inflamm Bowel Dis. 2005 Nov;11 Suppl 1:S3-12. doi: 10.1097/01.mib.0000184852.84558.b2. Inflamm Bowel Dis. 2005. PMID: 16254481 Review.
NOD2 mutations and anti-Saccharomyces cerevisiae antibodies are risk factors for Crohn's disease in African Americans.
Dassopoulos T, Nguyen GC, Talor MV, Datta LW, Isaacs KL, Lewis JD, Gold MS, Valentine JF, Smoot DT, Harris ML, Oliva-Hemker M, Bayless TM; NIDDK IBD Genetics Consortium; Burek CL, Brant SR. Dassopoulos T, et al. Among authors: lewis jd. Am J Gastroenterol. 2010 Feb;105(2):378-86. doi: 10.1038/ajg.2009.575. Epub 2009 Oct 13. Am J Gastroenterol. 2010. PMID: 19826411 Free PMC article.
Efficacy of methotrexate in ulcerative colitis: failure or promise.
Herfarth HH, Osterman MT, Isaacs KL, Lewis JD, Sands BE. Herfarth HH, et al. Among authors: lewis jd. Inflamm Bowel Dis. 2010 Aug;16(8):1421-30. doi: 10.1002/ibd.21246. Inflamm Bowel Dis. 2010. PMID: 20186931 Free PMC article. Review.
Contribution of higher risk genes and European admixture to Crohn's disease in African Americans.
Wang MH, Okazaki T, Kugathasan S, Cho JH, Isaacs KL, Lewis JD, Smoot DT, Valentine JF, Kader HA, Ford JG, Harris ML, Oliva-Hemker M, Cuffari C, Torbenson MS, Duerr RH, Silverberg MS, Rioux JD, Taylor KD, Nguyen GC, Wu Y, Datta LW, Hooker S, Dassopoulos T, Kittles RA, Kao LW, Brant SR. Wang MH, et al. Among authors: lewis jd. Inflamm Bowel Dis. 2012 Dec;18(12):2277-87. doi: 10.1002/ibd.22931. Epub 2012 Mar 12. Inflamm Bowel Dis. 2012. PMID: 22411504 Free PMC article.
1,173 results