Lewis I - Search Results

1

Identification of a PCSK9-LDLR disruptor peptide with in vivo function.

Brousseau ME, Clairmont KB, Spraggon G, Flyer AN, Golosov AA, Grosche P, Amin J, Andre J, Burdick D, Caplan S, Chen G, Chopra R, Ames L, Dubiel D, Fan L, Gattlen R, Kelly-Sullivan D, Koch AW, Lewis I, Li J, Liu E, Lubicka D, Marzinzik A, Nakajima K, Nettleton D, Ottl J, Pan M, Patel T, Perry L, Pickett S, Poirier J, Reid PC, Pelle X, Seepersaud M, Subramanian V, Vera V, Xu M, Yang L, Yang Q, Yu J, Zhu G, Monovich LG. Brousseau ME, et al. Among authors: lewis i. Cell Chem Biol. 2022 Feb 17;29(2):249-258.e5. doi: 10.1016/j.chembiol.2021.08.012. Epub 2021 Sep 20. Cell Chem Biol. 2022. PMID: 34547225 Free article.

2

Recent trends and observations in the design of high-quality screening collections.

Renner S, Popov M, Schuffenhauer A, Roth HJ, Breitenstein W, Marzinzik A, Lewis I, Krastel P, Nigsch F, Jenkins J, Jacoby E. Renner S, et al. Among authors: lewis i. Future Med Chem. 2011 Apr;3(6):751-66. doi: 10.4155/fmc.11.15. Future Med Chem. 2011. PMID: 21554080 Review.

3

Structure-based design of potent linear peptide inhibitors of the YAP-TEAD protein-protein interaction derived from the YAP omega-loop sequence.

Furet P, Salem B, Mesrouze Y, Schmelzle T, Lewis I, Kallen J, Chène P. Furet P, et al. Among authors: lewis i. Bioorg Med Chem Lett. 2019 Aug 15;29(16):2316-2319. doi: 10.1016/j.bmcl.2019.06.022. Epub 2019 Jun 18. Bioorg Med Chem Lett. 2019. PMID: 31235263

4

Special ergolines efficiently inhibit the chemokine receptor CXCR3 in blood.

Thoma G, Baenteli R, Lewis I, Jones D, Kovarik J, Streiff MB, Zerwes HG. Thoma G, et al. Among authors: lewis i. Bioorg Med Chem Lett. 2011 Aug 15;21(16):4745-9. doi: 10.1016/j.bmcl.2011.06.070. Epub 2011 Jun 29. Bioorg Med Chem Lett. 2011. PMID: 21764306

5

Drug design at peptide receptors: somatostatin receptor ligands.

Hannon JP, Nunn C, Stolz B, Bruns C, Weckbecker G, Lewis I, Troxler T, Hurth K, Hoyer D. Hannon JP, et al. Among authors: lewis i. J Mol Neurosci. 2002 Feb-Apr;18(1-2):15-27. doi: 10.1385/JMN:18:1-2:15. J Mol Neurosci. 2002. PMID: 11931345 Review.

6

A novel somatostatin mimic with broad somatotropin release inhibitory factor receptor binding and superior therapeutic potential.

Lewis I, Bauer W, Albert R, Chandramouli N, Pless J, Weckbecker G, Bruns C. Lewis I, et al. J Med Chem. 2003 Jun 5;46(12):2334-44. doi: 10.1021/jm021093t. J Med Chem. 2003. PMID: 12773038

7

Special ergolines are highly selective, potent antagonists of the chemokine receptor CXCR3: discovery, characterization and preliminary SAR of a promising lead.

Thoma G, Baenteli R, Lewis I, Wagner T, Oberer L, Blum W, Glickman F, Streiff MB, Zerwes HG. Thoma G, et al. Among authors: lewis i. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6185-8. doi: 10.1016/j.bmcl.2009.09.002. Epub 2009 Sep 6. Bioorg Med Chem Lett. 2009. PMID: 19783143

8

SOM230: a novel somatostatin peptidomimetic with broad somatotropin release inhibiting factor (SRIF) receptor binding and a unique antisecretory profile.

Bruns C, Lewis I, Briner U, Meno-Tetang G, Weckbecker G. Bruns C, et al. Among authors: lewis i. Eur J Endocrinol. 2002 May;146(5):707-16. doi: 10.1530/eje.0.1460707. Eur J Endocrinol. 2002. PMID: 11980628

9

SOM230: a new therapeutic modality for Cushing's disease.

Lewis I, Schmid HA, Kneuer R, Hoyer D, Silva AP, Weckbecker G, Bruns C, Pless J. Lewis I, et al. Chimia (Aarau). 2014;68(7-8):483-4. doi: 10.2533/chimia.2014.483. Chimia (Aarau). 2014. PMID: 25437387 Free article.

10

Discovery of novel pyrrolidineoxy-substituted heteroaromatics as potent and selective PI3K delta inhibitors with improved physicochemical properties.

Hoegenauer K, Soldermann N, Hebach C, Hollingworth GJ, Lewis I, von Matt A, Smith AB, Wolf RM, Wilcken R, Haasen D, Burkhart C, Zécri F. Hoegenauer K, et al. Among authors: lewis i. Bioorg Med Chem Lett. 2016 Dec 1;26(23):5657-5662. doi: 10.1016/j.bmcl.2016.10.069. Epub 2016 Oct 27. Bioorg Med Chem Lett. 2016. PMID: 27816514

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

706 results

Search Page