Lewin AS - Search Results

1

Delivery of CR2-fH Using AAV Vector Therapy as Treatment Strategy in the Mouse Model of Choroidal Neovascularization.

Schnabolk G, Parsons N, Obert E, Annamalai B, Nasarre C, Tomlinson S, Lewin AS, Rohrer B. Schnabolk G, et al. Among authors: lewin as. Mol Ther Methods Clin Dev. 2017 Nov 10;9:1-11. doi: 10.1016/j.omtm.2017.11.003. eCollection 2018 Jun 15. Mol Ther Methods Clin Dev. 2017. PMID: 29234687 Free PMC article.

2

Downregulation of p22phox in retinal pigment epithelial cells inhibits choroidal neovascularization in mice.

Li Q, Dinculescu A, Shan Z, Miller R, Pang J, Lewin AS, Raizada MK, Hauswirth WW. Li Q, et al. Among authors: lewin as. Mol Ther. 2008 Oct;16(10):1688-94. doi: 10.1038/mt.2008.164. Epub 2008 Jul 29. Mol Ther. 2008. PMID: 18665154 Free PMC article.

3

Cell-specific gene therapy driven by an optimized hypoxia-regulated vector reduces choroidal neovascularization.

Biswal MR, Prentice HM, Smith GW, Zhu P, Tong Y, Dorey CK, Lewin AS, Blanks JC. Biswal MR, et al. Among authors: lewin as. J Mol Med (Berl). 2018 Oct;96(10):1107-1118. doi: 10.1007/s00109-018-1683-0. Epub 2018 Aug 13. J Mol Med (Berl). 2018. PMID: 30105447

4

Expression of a CARD Slows the Retinal Degeneration of a Geographic Atrophy Mouse Model.

Young BM, Jones K, Massengill MT, Walsh E, Li H, Lewin AS, Ildefonso CJ. Young BM, et al. Among authors: lewin as. Mol Ther Methods Clin Dev. 2019 Jun 12;14:113-125. doi: 10.1016/j.omtm.2019.06.001. eCollection 2019 Sep 13. Mol Ther Methods Clin Dev. 2019. PMID: 31334304 Free PMC article.

5

AAV Mediated Delivery of Myxoma Virus M013 Gene Protects the Retina against Autoimmune Uveitis.

Ridley RB, Young BM, Lee J, Walsh E, Ahmed CM, Lewin AS, Ildefonso CJ. Ridley RB, et al. Among authors: lewin as. J Clin Med. 2019 Nov 29;8(12):2082. doi: 10.3390/jcm8122082. J Clin Med. 2019. PMID: 31795515 Free PMC article.

6

Knockdown of wild-type mouse rhodopsin using an AAV vectored ribozyme as part of an RNA replacement approach.

Gorbatyuk MS, Pang JJ, Thomas J Jr, Hauswirth WW, Lewin AS. Gorbatyuk MS, et al. Among authors: lewin as. Mol Vis. 2005 Aug 29;11:648-56. Mol Vis. 2005. PMID: 16145542 Free article.

7

Suppression of mouse rhodopsin expression in vivo by AAV mediated siRNA delivery.

Gorbatyuk M, Justilien V, Liu J, Hauswirth WW, Lewin AS. Gorbatyuk M, et al. Among authors: lewin as. Vision Res. 2007 Apr;47(9):1202-8. doi: 10.1016/j.visres.2006.11.026. Epub 2007 Feb 12. Vision Res. 2007. PMID: 17292939 Free PMC article.

8

SOD2 knockdown mouse model of early AMD.

Justilien V, Pang JJ, Renganathan K, Zhan X, Crabb JW, Kim SR, Sparrow JR, Hauswirth WW, Lewin AS. Justilien V, et al. Among authors: lewin as. Invest Ophthalmol Vis Sci. 2007 Oct;48(10):4407-20. doi: 10.1167/iovs.07-0432. Invest Ophthalmol Vis Sci. 2007. PMID: 17898259 Free PMC article.

9

High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors.

Petrs-Silva H, Dinculescu A, Li Q, Min SH, Chiodo V, Pang JJ, Zhong L, Zolotukhin S, Srivastava A, Lewin AS, Hauswirth WW. Petrs-Silva H, et al. Among authors: lewin as. Mol Ther. 2009 Mar;17(3):463-71. doi: 10.1038/mt.2008.269. Epub 2008 Dec 16. Mol Ther. 2009. PMID: 19066593 Free PMC article.

10

Novel properties of tyrosine-mutant AAV2 vectors in the mouse retina.

Petrs-Silva H, Dinculescu A, Li Q, Deng WT, Pang JJ, Min SH, Chiodo V, Neeley AW, Govindasamy L, Bennett A, Agbandje-McKenna M, Zhong L, Li B, Jayandharan GR, Srivastava A, Lewin AS, Hauswirth WW. Petrs-Silva H, et al. Among authors: lewin as. Mol Ther. 2011 Feb;19(2):293-301. doi: 10.1038/mt.2010.234. Epub 2010 Nov 2. Mol Ther. 2011. PMID: 21045809 Free PMC article.

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