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343 results

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Inhibition of advanced glycation end product formation and serum protein infiltration in bioprosthetic heart valve leaflets: Investigations of anti-glycation agents and anticalcification interactions with ethanol pretreatment.
Zakharchenko A, Rock CA, Thomas TE, Keeney S, Hall EJ, Takano H, Krieger AM, Ferrari G, Levy RJ. Zakharchenko A, et al. Among authors: levy rj. Biomaterials. 2022 Oct;289:121782. doi: 10.1016/j.biomaterials.2022.121782. Epub 2022 Sep 6. Biomaterials. 2022. PMID: 36099713 Free PMC article.
The susceptibility of bioprosthetic heart valve leaflets to oxidation.
Christian AJ, Lin H, Alferiev IS, Connolly JM, Ferrari G, Hazen SL, Ischiropoulos H, Levy RJ. Christian AJ, et al. Among authors: levy rj. Biomaterials. 2014 Feb;35(7):2097-102. doi: 10.1016/j.biomaterials.2013.11.045. Epub 2013 Dec 18. Biomaterials. 2014. PMID: 24360721 Free PMC article.
Glycation and Serum Albumin Infiltration Contribute to the Structural Degeneration of Bioprosthetic Heart Valves.
Frasca A, Xue Y, Kossar AP, Keeney S, Rock C, Zakharchenko A, Streeter M, Gorman RC, Grau JB, George I, Bavaria JE, Krieger A, Spiegel DA, Levy RJ, Ferrari G. Frasca A, et al. Among authors: levy rj. JACC Basic Transl Sci. 2020 Aug 5;5(8):755-766. doi: 10.1016/j.jacbts.2020.06.008. eCollection 2020 Aug. JACC Basic Transl Sci. 2020. PMID: 32875167 Free PMC article.
Model studies of advanced glycation end product modification of heterograft biomaterials: The effects of in vitro glucose, glyoxal, and serum albumin on collagen structure and mechanical properties.
Rock CA, Keeney S, Zakharchenko A, Takano H, Spiegel DA, Krieger AM, Ferrari G, Levy RJ. Rock CA, et al. Among authors: levy rj. Acta Biomater. 2021 Mar 15;123:275-285. doi: 10.1016/j.actbio.2020.12.053. Epub 2021 Jan 11. Acta Biomater. 2021. PMID: 33444798 Free PMC article.
Poly-2-methyl-2-oxazoline-modified bioprosthetic heart valve leaflets have enhanced biocompatibility and resist structural degeneration.
Zakharchenko A, Xue Y, Keeney S, Rock CA, Alferiev IS, Stachelek SJ, Takano H, Thomas T, Nagaswami C, Krieger AM, Chorny M, Ferrari G, Levy RJ. Zakharchenko A, et al. Among authors: levy rj. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2120694119. doi: 10.1073/pnas.2120694119. Proc Natl Acad Sci U S A. 2022. PMID: 35131859 Free PMC article.
Noncalcific Mechanisms of Bioprosthetic Structural Valve Degeneration.
Marro M, Kossar AP, Xue Y, Frasca A, Levy RJ, Ferrari G. Marro M, et al. Among authors: levy rj. J Am Heart Assoc. 2021 Feb 2;10(3):e018921. doi: 10.1161/JAHA.120.018921. Epub 2021 Jan 26. J Am Heart Assoc. 2021. PMID: 33494616 Free PMC article. Review.
Age-related enhanced degeneration of bioprosthetic valves due to leaflet calcification, tissue crosslinking, and structural changes.
Xue Y, Kossar AP, Abramov A, Frasca A, Sun M, Zyablitskaya M, Paik D, Kalfa D, Della Barbera M, Thiene G, Kozaki S, Kawashima T, Gorman JH, Gorman RC, Gillespie MJ, Carreon CK, Sanders SP, Levy RJ, Ferrari G. Xue Y, et al. Among authors: levy rj. Cardiovasc Res. 2023 Mar 17;119(1):302-315. doi: 10.1093/cvr/cvac002. Cardiovasc Res. 2023. PMID: 35020813 Free PMC article.
343 results