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Self-renewing resident arterial macrophages arise from embryonic CX3CR1(+) precursors and circulating monocytes immediately after birth.
Ensan S, Li A, Besla R, Degousee N, Cosme J, Roufaiel M, Shikatani EA, El-Maklizi M, Williams JW, Robins L, Li C, Lewis B, Yun TJ, Lee JS, Wieghofer P, Khattar R, Farrokhi K, Byrne J, Ouzounian M, Zavitz CC, Levy GA, Bauer CM, Libby P, Husain M, Swirski FK, Cheong C, Prinz M, Hilgendorf I, Randolph GJ, Epelman S, Gramolini AO, Cybulsky MI, Rubin BB, Robbins CS. Ensan S, et al. Among authors: levy ga. Nat Immunol. 2016 Feb;17(2):159-68. doi: 10.1038/ni.3343. Epub 2015 Dec 7. Nat Immunol. 2016. PMID: 26642357
Inhibition of the Fibrinogen-Like Protein 2:FcγRIIB/RIII immunosuppressive pathway enhances antiviral T-cell and B-cell responses leading to clearance of lymphocytic choriomeningitis virus clone 13.
Luft O, Khattar R, Farrokhi K, Ferri D, Yavorska N, Zhang J, Sadozai H, Adeyi O, Chruscinski A, Levy GA, Selzner N. Luft O, et al. Among authors: levy ga. Immunology. 2018 Jul;154(3):476-489. doi: 10.1111/imm.12897. Epub 2018 Feb 20. Immunology. 2018. PMID: 29341118 Free PMC article.
The FGL2-FcgammaRIIB pathway: a novel mechanism leading to immunosuppression.
Liu H, Shalev I, Manuel J, He W, Leung E, Crookshank J, Liu MF, Diao J, Cattral M, Clark DA, Isenman DE, Gorczynski RM, Grant DR, Zhang L, Phillips MJ, Cybulsky MI, Levy GA. Liu H, et al. Among authors: levy ga. Eur J Immunol. 2008 Nov;38(11):3114-26. doi: 10.1002/eji.200838338. Eur J Immunol. 2008. PMID: 18991288 Free article.
Targeted deletion of fgl2 leads to impaired regulatory T cell activity and development of autoimmune glomerulonephritis.
Shalev I, Liu H, Koscik C, Bartczak A, Javadi M, Wong KM, Maknojia A, He W, Liu MF, Diao J, Winter E, Manuel J, McCarthy D, Cattral M, Gommerman J, Clark DA, Phillips MJ, Gorczynski RR, Zhang L, Downey G, Grant D, Cybulsky MI, Levy G. Shalev I, et al. J Immunol. 2008 Jan 1;180(1):249-60. doi: 10.4049/jimmunol.180.1.249. J Immunol. 2008. PMID: 18097026
The regulatory T cell effector molecule fibrinogen-like protein 2 is necessary for the development of rapamycin-induced tolerance to fully MHC-mismatched murine cardiac allografts.
Urbanellis P, Shyu W, Khattar R, Wang J, Zakharova A, He W, Sadozai H, Amir AZ, Shalev I, Phillips MJ, Adeyi O, Ross H, Grant D, Levy GA, Chruscinski A. Urbanellis P, et al. Among authors: levy ga. Immunology. 2015 Jan;144(1):91-106. doi: 10.1111/imm.12354. Immunology. 2015. PMID: 24990517 Free PMC article.
291 results