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Nrf2 gene transfer induces antioxidant enzymes and suppresses smooth muscle cell growth in vitro and reduces oxidative stress in rabbit aorta in vivo.
Levonen AL, Inkala M, Heikura T, Jauhiainen S, Jyrkkänen HK, Kansanen E, Määttä K, Romppanen E, Turunen P, Rutanen J, Ylä-Herttuala S. Levonen AL, et al. Arterioscler Thromb Vasc Biol. 2007 Apr;27(4):741-7. doi: 10.1161/01.ATV.0000258868.80079.4d. Epub 2007 Jan 25. Arterioscler Thromb Vasc Biol. 2007. PMID: 17255530
Enhanced polyamine catabolism alters homeostatic control of white adipose tissue mass, energy expenditure, and glucose metabolism.
Pirinen E, Kuulasmaa T, Pietilä M, Heikkinen S, Tusa M, Itkonen P, Boman S, Skommer J, Virkamäki A, Hohtola E, Kettunen M, Fatrai S, Kansanen E, Koota S, Niiranen K, Parkkinen J, Levonen AL, Ylä-Herttuala S, Hiltunen JK, Alhonen L, Smith U, Jänne J, Laakso M. Pirinen E, et al. Among authors: levonen al. Mol Cell Biol. 2007 Jul;27(13):4953-67. doi: 10.1128/MCB.02034-06. Epub 2007 May 7. Mol Cell Biol. 2007. PMID: 17485446 Free PMC article.
Extracellular superoxide dismutase accelerates endothelial recovery and inhibits in-stent restenosis in stented atherosclerotic Watanabe heritable hyperlipidemic rabbit aorta.
Bräsen JH, Leppänen O, Inkala M, Heikura T, Levin M, Ahrens F, Rutanen J, Pietsch H, Bergqvist D, Levonen AL, Basu S, Zeller T, Klöppel G, Laukkanen MO, Ylä-Herttuala S. Bräsen JH, et al. Among authors: levonen al. J Am Coll Cardiol. 2007 Dec 4;50(23):2249-53. doi: 10.1016/j.jacc.2007.08.038. Epub 2007 Nov 19. J Am Coll Cardiol. 2007. PMID: 18061074 Free article.
Nrf2 regulates antioxidant gene expression evoked by oxidized phospholipids in endothelial cells and murine arteries in vivo.
Jyrkkänen HK, Kansanen E, Inkala M, Kivelä AM, Hurttila H, Heinonen SE, Goldsteins G, Jauhiainen S, Tiainen S, Makkonen H, Oskolkova O, Afonyushkin T, Koistinaho J, Yamamoto M, Bochkov VN, Ylä-Herttuala S, Levonen AL. Jyrkkänen HK, et al. Among authors: levonen al. Circ Res. 2008 Jul 3;103(1):e1-9. doi: 10.1161/CIRCRESAHA.108.176883. Epub 2008 Jun 5. Circ Res. 2008. PMID: 18535259
98 results