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Pharmacological elevation of sphingosine-1-phosphate by S1P lyase inhibition accelerates bone regeneration after post-traumatic osteomyelitis.
Wagner JM, Wille A, Fueth M, Weske S, Lotzien S, Reinkemeier F, Wallner C, Sogorski A, Dittfeld S, Becerikli M, Schildhauer TA, Lehnhardt M, Levkau B, Behr B. Wagner JM, et al. Among authors: levkau b. J Cell Mol Med. 2023 Dec;27(23):3786-3795. doi: 10.1111/jcmm.17952. Epub 2023 Sep 14. J Cell Mol Med. 2023. PMID: 37710406 Free PMC article.
Characterization of the dehydrogenase-reductase DHRS2 and its involvement in histone deacetylase inhibition in urological malignancies.
Müller MR, Burmeister A, Skowron MA, Stephan A, Söhngen C, Wollnitzke P, Petzsch P, Alves Avelar LA, Kurz T, Köhrer K, Levkau B, Nettersheim D. Müller MR, et al. Among authors: levkau b. Exp Cell Res. 2024 May 3;439(1):114055. doi: 10.1016/j.yexcr.2024.114055. Online ahead of print. Exp Cell Res. 2024. PMID: 38704080 Free article.
SYSTEMI - systemic organ communication in STEMI: design and rationale of a cohort study of patients with ST-segment elevation myocardial infarction.
Bönner F, Jung C, Polzin A, Erkens R, Dannenberg L, Ipek R, Kaldirim M, Cramer M, Wischmann P, Zaharia OP, Meyer C, Flögel U, Levkau B, Gödecke A, Fischer J, Klöcker N, Krüger M, Roden M, Kelm M. Bönner F, et al. Among authors: levkau b. BMC Cardiovasc Disord. 2023 May 3;23(1):232. doi: 10.1186/s12872-023-03210-1. BMC Cardiovasc Disord. 2023. PMID: 37138228 Free PMC article.
The mycotoxin viriditoxin induces leukemia- and lymphoma-specific apoptosis by targeting mitochondrial metabolism.
Stuhldreier F, Schmitt L, Lenz T, Hinxlage I, Zimmermann M, Wollnitzke P, Schliehe-Diecks J, Liu Y, Jäger P, Geyh S, Teusch N, Peter C, Bhatia S, Haas R, Levkau B, Reichert AS, Stühler K, Proksch P, Stork B, Wesselborg S. Stuhldreier F, et al. Among authors: levkau b. Cell Death Dis. 2022 Nov 8;13(11):938. doi: 10.1038/s41419-022-05356-w. Cell Death Dis. 2022. PMID: 36347842 Free PMC article.
Sublethal necroptosis signaling promotes inflammation and liver cancer.
Vucur M, Ghallab A, Schneider AT, Adili A, Cheng M, Castoldi M, Singer MT, Büttner V, Keysberg LS, Küsgens L, Kohlhepp M, Görg B, Gallage S, Barragan Avila JE, Unger K, Kordes C, Leblond AL, Albrecht W, Loosen SH, Lohr C, Jördens MS, Babler A, Hayat S, Schumacher D, Koenen MT, Govaere O, Boekschoten MV, Jörs S, Villacorta-Martin C, Mazzaferro V, Llovet JM, Weiskirchen R, Kather JN, Starlinger P, Trauner M, Luedde M, Heij LR, Neumann UP, Keitel V, Bode JG, Schneider RK, Tacke F, Levkau B, Lammers T, Fluegen G, Alexandrov T, Collins AL, Nelson G, Oakley F, Mann DA, Roderburg C, Longerich T, Weber A, Villanueva A, Samson AL, Murphy JM, Kramann R, Geisler F, Costa IG, Hengstler JG, Heikenwalder M, Luedde T. Vucur M, et al. Among authors: levkau b. Immunity. 2023 Jul 11;56(7):1578-1595.e8. doi: 10.1016/j.immuni.2023.05.017. Epub 2023 Jun 16. Immunity. 2023. PMID: 37329888 Free article.
Identification of myeloid-derived growth factor as a mechanically-induced, growth-promoting angiocrine signal for human hepatocytes.
Große-Segerath L, Follert P, Behnke K, Ettich J, Buschmann T, Kirschner P, Hartwig S, Lehr S, Korf-Klingebiel M, Eberhard D, Lehwald-Tywuschik N, Al-Hasani H, Knoefel WT, Heinrich S, Levkau B, Wollert KC, Scheller J, Lammert E. Große-Segerath L, et al. Among authors: levkau b. Nat Commun. 2024 Feb 5;15(1):1076. doi: 10.1038/s41467-024-44760-y. Nat Commun. 2024. PMID: 38316785 Free PMC article.
Sphingosine-1-phosphate suppresses GLUT activity through PP2A and counteracts hyperglycemia in diabetic red blood cells.
Thomas N, Schröder NH, Nowak MK, Wollnitzke P, Ghaderi S, von Wnuck Lipinski K, Wille A, Deister-Jonas J, Vogt J, Gräler MH, Dannenberg L, Buschmann T, Westhoff P, Polzin A, Kelm M, Keul P, Weske S, Levkau B. Thomas N, et al. Among authors: levkau b. Nat Commun. 2023 Dec 14;14(1):8329. doi: 10.1038/s41467-023-44109-x. Nat Commun. 2023. PMID: 38097610 Free PMC article.
165 results