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SMARCA4 loss is synthetic lethal with CDK4/6 inhibition in non-small cell lung cancer.
Xue Y, Meehan B, Fu Z, Wang XQD, Fiset PO, Rieker R, Levins C, Kong T, Zhu X, Morin G, Skerritt L, Herpel E, Venneti S, Martinez D, Judkins AR, Jung S, Camilleri-Broet S, Gonzalez AV, Guiot MC, Lockwood WW, Spicer JD, Agaimy A, Pastor WA, Dostie J, Rak J, Foulkes WD, Huang S. Xue Y, et al. Among authors: levins c. Nat Commun. 2019 Feb 4;10(1):557. doi: 10.1038/s41467-019-08380-1. Nat Commun. 2019. PMID: 30718506 Free PMC article.
In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight.
Dahlman JE, Barnes C, Khan O, Thiriot A, Jhunjunwala S, Shaw TE, Xing Y, Sager HB, Sahay G, Speciner L, Bader A, Bogorad RL, Yin H, Racie T, Dong Y, Jiang S, Seedorf D, Dave A, Sandu KS, Webber MJ, Novobrantseva T, Ruda VM, Lytton-Jean AKR, Levins CG, Kalish B, Mudge DK, Perez M, Abezgauz L, Dutta P, Smith L, Charisse K, Kieran MW, Fitzgerald K, Nahrendorf M, Danino D, Tuder RM, von Andrian UH, Akinc A, Schroeder A, Panigrahy D, Kotelianski V, Langer R, Anderson DG. Dahlman JE, et al. Among authors: levins cg. Nat Nanotechnol. 2014 Aug;9(8):648-655. doi: 10.1038/nnano.2014.84. Epub 2014 May 11. Nat Nanotechnol. 2014. PMID: 24813696 Free PMC article.
Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells.
Novobrantseva TI, Borodovsky A, Wong J, Klebanov B, Zafari M, Yucius K, Querbes W, Ge P, Ruda VM, Milstein S, Speciner L, Duncan R, Barros S, Basha G, Cullis P, Akinc A, Donahoe JS, Narayanannair Jayaprakash K, Jayaraman M, Bogorad RL, Love K, Whitehead K, Levins C, Manoharan M, Swirski FK, Weissleder R, Langer R, Anderson DG, de Fougerolles A, Nahrendorf M, Koteliansky V. Novobrantseva TI, et al. Among authors: levins c. Mol Ther Nucleic Acids. 2012 Jan 24;1(1):e4. doi: 10.1038/mtna.2011.3. Mol Ther Nucleic Acids. 2012. PMID: 23344621 Free PMC article.
Remotely activated protein-producing nanoparticles.
Schroeder A, Goldberg MS, Kastrup C, Wang Y, Jiang S, Joseph BJ, Levins CG, Kannan ST, Langer R, Anderson DG. Schroeder A, et al. Among authors: levins cg. Nano Lett. 2012 Jun 13;12(6):2685-9. doi: 10.1021/nl2036047. Epub 2012 May 8. Nano Lett. 2012. PMID: 22432731 Free PMC article.
Alkane-modified short polyethyleneimine for siRNA delivery.
Schroeder A, Dahlman JE, Sahay G, Love KT, Jiang S, Eltoukhy AA, Levins CG, Wang Y, Anderson DG. Schroeder A, et al. Among authors: levins cg. J Control Release. 2012 Jun 10;160(2):172-6. doi: 10.1016/j.jconrel.2011.11.030. Epub 2011 Dec 2. J Control Release. 2012. PMID: 22155553 Free PMC article.
Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery.
Siegwart DJ, Whitehead KA, Nuhn L, Sahay G, Cheng H, Jiang S, Ma M, Lytton-Jean A, Vegas A, Fenton P, Levins CG, Love KT, Lee H, Cortez C, Collins SP, Li YF, Jang J, Querbes W, Zurenko C, Novobrantseva T, Langer R, Anderson DG. Siegwart DJ, et al. Among authors: levins cg. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):12996-3001. doi: 10.1073/pnas.1106379108. Epub 2011 Jul 22. Proc Natl Acad Sci U S A. 2011. PMID: 21784981 Free PMC article.
Lipid-like materials for low-dose, in vivo gene silencing.
Love KT, Mahon KP, Levins CG, Whitehead KA, Querbes W, Dorkin JR, Qin J, Cantley W, Qin LL, Racie T, Frank-Kamenetsky M, Yip KN, Alvarez R, Sah DW, de Fougerolles A, Fitzgerald K, Koteliansky V, Akinc A, Langer R, Anderson DG. Love KT, et al. Among authors: levins cg. Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):1864-9. doi: 10.1073/pnas.0910603106. Epub 2010 Jan 11. Proc Natl Acad Sci U S A. 2010. PMID: 20080679 Free PMC article.
Lipid-based nanotherapeutics for siRNA delivery.
Schroeder A, Levins CG, Cortez C, Langer R, Anderson DG. Schroeder A, et al. Among authors: levins cg. J Intern Med. 2010 Jan;267(1):9-21. doi: 10.1111/j.1365-2796.2009.02189.x. J Intern Med. 2010. PMID: 20059641 Free PMC article. Review.
16 results