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Clonally stable Vκ allelic choice instructs Igκ repertoire.
Levin-Klein R, Fraenkel S, Lichtenstein M, Matheson LS, Bartok O, Nevo Y, Kadener S, Corcoran AE, Cedar H, Bergman Y. Levin-Klein R, et al. Nat Commun. 2017 May 30;8:15575. doi: 10.1038/ncomms15575. Nat Commun. 2017. PMID: 28555639 Free PMC article.
Postnatal DNA demethylation and its role in tissue maturation.
Reizel Y, Sabag O, Skversky Y, Spiro A, Steinberg B, Bernstein D, Wang A, Kieckhaefer J, Li C, Pikarsky E, Levin-Klein R, Goren A, Rajewsky K, Kaestner KH, Cedar H. Reizel Y, et al. Among authors: levin klein r. Nat Commun. 2018 May 23;9(1):2040. doi: 10.1038/s41467-018-04456-6. Nat Commun. 2018. PMID: 29795194 Free PMC article.
A novel pax5-binding regulatory element in the igκ locus.
Levin-Klein R, Kirillov A, Rosenbluh C, Cedar H, Bergman Y. Levin-Klein R, et al. Front Immunol. 2014 May 23;5:240. doi: 10.3389/fimmu.2014.00240. eCollection 2014. Front Immunol. 2014. PMID: 24904588 Free PMC article.
Tissue-specific DNA demethylation is required for proper B-cell differentiation and function.
Orlanski S, Labi V, Reizel Y, Spiro A, Lichtenstein M, Levin-Klein R, Koralov SB, Skversky Y, Rajewsky K, Cedar H, Bergman Y. Orlanski S, et al. Among authors: levin klein r. Proc Natl Acad Sci U S A. 2016 May 3;113(18):5018-23. doi: 10.1073/pnas.1604365113. Epub 2016 Apr 18. Proc Natl Acad Sci U S A. 2016. PMID: 27091986 Free PMC article.
APOBEC3A drives deaminase domain-independent chromosomal instability to promote pancreatic cancer metastasis.
Wörmann SM, Zhang A, Thege FI, Cowan RW, Rupani DN, Wang R, Manning SL, Gates C, Wu W, Levin-Klein R, Rajapakshe KI, Yu M, Multani AS, Kang Y, Taniguchi CM, Schlacher K, Bellin MD, Katz MHG, Kim MP, Fleming JB, Gallinger S, Maddipati R, Harris RS, Notta F, Ross SR, Maitra A, Rhim AD. Wörmann SM, et al. Among authors: levin klein r. Nat Cancer. 2021 Dec;2(12):1338-1356. doi: 10.1038/s43018-021-00268-8. Epub 2021 Nov 18. Nat Cancer. 2021. PMID: 35121902
APOBEC3A catalyzes mutation and drives carcinogenesis in vivo.
Law EK, Levin-Klein R, Jarvis MC, Kim H, Argyris PP, Carpenter MA, Starrett GJ, Temiz NA, Larson LK, Durfee C, Burns MB, Vogel RI, Stavrou S, Aguilera AN, Wagner S, Largaespada DA, Starr TK, Ross SR, Harris RS. Law EK, et al. Among authors: levin klein r. J Exp Med. 2020 Dec 7;217(12):e20200261. doi: 10.1084/jem.20200261. J Exp Med. 2020. PMID: 32870257 Free PMC article.
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