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Cardiomyocyte-specific PCSK9 deficiency compromises mitochondrial bioenergetics and heart function.
Laudette M, Lindbom M, Arif M, Cinato M, Ruiz M, Doran S, Miljanovic A, Rutberg M, Andersson L, Klevstig M, Henricsson M, Bergh PO, Bollano E, Aung N, Gustav Smith J, Pilon M, Hyötyläinen T, Orešič M, Perkins R, Mardinoglu A, Levin MC, Borén J. Laudette M, et al. Among authors: levin mc. Cardiovasc Res. 2023 Jul 4;119(7):1537-1552. doi: 10.1093/cvr/cvad041. Cardiovasc Res. 2023. PMID: 36880401 Free PMC article.
ApoCIII-enriched LDL in type 2 diabetes displays altered lipid composition, increased susceptibility for sphingomyelinase, and increased binding to biglycan.
Hiukka A, Ståhlman M, Pettersson C, Levin M, Adiels M, Teneberg S, Leinonen ES, Hultén LM, Wiklund O, Oresic M, Olofsson SO, Taskinen MR, Ekroos K, Borén J. Hiukka A, et al. Diabetes. 2009 Sep;58(9):2018-26. doi: 10.2337/db09-0206. Epub 2009 Jun 5. Diabetes. 2009. PMID: 19502413 Free PMC article.
Rip2 deficiency leads to increased atherosclerosis despite decreased inflammation.
Levin MC, Jirholt P, Wramstedt A, Johansson ME, Lundberg AM, Trajkovska MG, Ståhlman M, Fogelstrand P, Brisslert M, Fogelstrand L, Yan ZQ, Hansson GK, Björkbacka H, Olofsson SO, Borén J. Levin MC, et al. Circ Res. 2011 Nov 11;109(11):1210-8. doi: 10.1161/CIRCRESAHA.111.246702. Epub 2011 Sep 29. Circ Res. 2011. PMID: 21959219
132 results