Lever AML - Search Results

1

HIV-1 remission following CCR5Δ32/Δ32 haematopoietic stem-cell transplantation.

Gupta RK, Abdul-Jawad S, McCoy LE, Mok HP, Peppa D, Salgado M, Martinez-Picado J, Nijhuis M, Wensing AMJ, Lee H, Grant P, Nastouli E, Lambert J, Pace M, Salasc F, Monit C, Innes AJ, Muir L, Waters L, Frater J, Lever AML, Edwards SG, Gabriel IH, Olavarria E. Gupta RK, et al. Among authors: lever aml. Nature. 2019 Apr;568(7751):244-248. doi: 10.1038/s41586-019-1027-4. Epub 2019 Mar 5. Nature. 2019. PMID: 30836379 Free PMC article.

2

No evidence of ongoing evolution in replication competent latent HIV-1 in a patient followed up for two years.

Mok HP, Norton NJ, Hirst JC, Fun A, Bandara M, Wills MR, Lever AML. Mok HP, et al. Among authors: lever aml. Sci Rep. 2018 Feb 8;8(1):2639. doi: 10.1038/s41598-018-20682-w. Sci Rep. 2018. PMID: 29422601 Free PMC article.

3

A highly reproducible quantitative viral outgrowth assay for the measurement of the replication-competent latent HIV-1 reservoir.

Fun A, Mok HP, Wills MR, Lever AM. Fun A, et al. Sci Rep. 2017 Feb 24;7:43231. doi: 10.1038/srep43231. Sci Rep. 2017. PMID: 28233807 Free PMC article.

4

A novel, sensitive dual-indicator cell line for detection and quantification of inducible, replication-competent latent HIV-1 from reservoir cells.

Salasc F, Gludish DW, Jarvis I, Boliar S, Wills MR, Russell DG, Lever AML, Mok HP. Salasc F, et al. Among authors: lever aml. Sci Rep. 2019 Dec 18;9(1):19325. doi: 10.1038/s41598-019-55596-8. Sci Rep. 2019. PMID: 31852924 Free PMC article.

5

Innovations in the quantitative virus outgrowth assay and its use in clinical trials.

Norton NJ, Fun A, Bandara M, Wills MR, Mok HP, Lever AML. Norton NJ, et al. Among authors: lever aml. Retrovirology. 2017 Dec 21;14(1):58. doi: 10.1186/s12977-017-0381-2. Retrovirology. 2017. PMID: 29268753 Free PMC article. Review.

6

HIV Silencing and Inducibility Are Heterogeneous and Are Affected by Factors Intrinsic to the Virus.

Norton NJ, Mok HP, Sharif F, Hirst JC, Lever AML. Norton NJ, et al. Among authors: lever aml. mBio. 2019 Jun 25;10(3):e00188-19. doi: 10.1128/mBio.00188-19. mBio. 2019. PMID: 31239371 Free PMC article.

7

Stable gene expression occurs from a minority of integrated HIV-1-based vectors: transcriptional silencing is present in the majority.

Mok HP, Javed S, Lever A. Mok HP, et al. Gene Ther. 2007 May;14(9):741-51. doi: 10.1038/sj.gt.3302923. Epub 2007 Mar 1. Gene Ther. 2007. PMID: 17330088

8

Incoming HIV virion-derived Gag Spacer Peptide 2 (p1) is a target of effective CD8⁺ T cell antiviral responses.

Yang H, Llano A, Cedeño S, von Delft A, Corcuera A, Gillespie GM, Knox A, Leneghan DB, Frater J, Stöhr W, Fidler S, Mothe B, Mak J, Brander C, Ternette N, Dorrell L; Research in Viral Eradication of Reservoirs (RIVER) trial study group. Yang H, et al. Cell Rep. 2021 May 11;35(6):109103. doi: 10.1016/j.celrep.2021.109103. Cell Rep. 2021. PMID: 33979627 Free article.

9

Vector integration: location, location, location.

Mok HP, Lever AM. Mok HP, et al. Gene Ther. 2005 Jan;12(1):1-2. doi: 10.1038/sj.gt.3302415. Gene Ther. 2005. PMID: 15510174 No abstract available.

10

Antiretroviral therapy alone versus antiretroviral therapy with a kick and kill approach, on measures of the HIV reservoir in participants with recent HIV infection (the RIVER trial): a phase 2, randomised trial.

Fidler S, Stöhr W, Pace M, Dorrell L, Lever A, Pett S, Kinloch-de Loes S, Fox J, Clarke A, Nelson M, Thornhill J, Khan M, Fun A, Bandara M, Kelly D, Kopycinski J, Hanke T, Yang H, Bennett R, Johnson M, Howell B, Barnard R, Wu G, Kaye S, Wills M, Babiker A, Frater J; RIVER trial study group. Fidler S, et al. Lancet. 2020 Mar 14;395(10227):888-898. doi: 10.1016/S0140-6736(19)32990-3. Epub 2020 Feb 19. Lancet. 2020. PMID: 32085823 Clinical Trial.

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