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Hydroxychloroquine Proves Ineffective in Hamsters and Macaques Infected with SARS-CoV-2.
Rosenke K, Jarvis MA, Feldmann F, Schwarz B, Okumura A, Lovaglio J, Saturday G, Hanley PW, Meade-White K, Williamson BN, Hansen F, Perez-Perez L, Leventhal S, Tang-Huau TL, Nason M, Callison J, Haddock E, Scott D, Sewell G, Bosio CM, Hawman D, de Wit E, Feldmann H. Rosenke K, et al. Among authors: leventhal s. bioRxiv [Preprint]. 2020 Jun 11:2020.06.10.145144. doi: 10.1101/2020.06.10.145144. bioRxiv. 2020. PMID: 32577633 Free PMC article. Preprint.
Single-dose replicating RNA vaccine induces neutralizing antibodies against SARS-CoV-2 in nonhuman primates.
Erasmus JH, Khandhar AP, Walls AC, Hemann EA, O'Connor MA, Murapa P, Archer J, Leventhal S, Fuller J, Lewis T, Draves KE, Randall S, Guerriero KA, Duthie MS, Carter D, Reed SG, Hawman DW, Feldmann H, Gale M, Veesler D, Berglund P, Fuller DH. Erasmus JH, et al. Among authors: leventhal s. bioRxiv [Preprint]. 2020 May 28:2020.05.28.121640. doi: 10.1101/2020.05.28.121640. bioRxiv. 2020. PMID: 32511417 Free PMC article. Preprint.
An Alphavirus-derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates.
Erasmus JH, Khandhar AP, O'Connor MA, Walls AC, Hemann EA, Murapa P, Archer J, Leventhal S, Fuller JT, Lewis TB, Draves KE, Randall S, Guerriero KA, Duthie MS, Carter D, Reed SG, Hawman DW, Feldmann H, Gale M Jr, Veesler D, Berglund P, Fuller DH. Erasmus JH, et al. Among authors: leventhal s. Sci Transl Med. 2020 Aug 5;12(555):eabc9396. doi: 10.1126/scitranslmed.abc9396. Epub 2020 Jul 20. Sci Transl Med. 2020. PMID: 32690628 Free PMC article.
Orally delivered MK-4482 inhibits SARS-CoV-2 replication in the Syrian hamster model.
Rosenke K, Hansen F, Schwarz B, Feldmann F, Haddock E, Rosenke R, Meade-White K, Okumura A, Leventhal S, Hawman DW, Ricotta E, Bosio CM, Saturday G, Feldmann H, Jarvis MA. Rosenke K, et al. Among authors: leventhal s. Res Sq [Preprint]. 2020 Oct 8:rs.3.rs-86289. doi: 10.21203/rs.3.rs-86289/v1. Res Sq. 2020. PMID: 33052329 Free PMC article. Updated. Preprint.
Hydroxychloroquine prophylaxis and treatment is ineffective in macaque and hamster SARS-CoV-2 disease models.
Rosenke K, Jarvis MA, Feldmann F, Schwarz B, Okumura A, Lovaglio J, Saturday G, Hanley PW, Meade-White K, Williamson BN, Hansen F, Perez-Perez L, Leventhal S, Tang-Huau TL, Callison J, Haddock E, Stromberg KA, Scott D, Sewell G, Bosio CM, Hawman D, de Wit E, Feldmann H. Rosenke K, et al. Among authors: leventhal s. JCI Insight. 2020 Dec 3;5(23):e143174. doi: 10.1172/jci.insight.143174. JCI Insight. 2020. PMID: 33090972 Free PMC article.
46 results