Leurs R - Search Results

1

The clinical pharmacology of non-sedating antihistamines.

Yanai K, Yoshikawa T, Yanai A, Nakamura T, Iida T, Leurs R, Tashiro M. Yanai K, et al. Among authors: leurs r. Pharmacol Ther. 2017 Oct;178:148-156. doi: 10.1016/j.pharmthera.2017.04.004. Epub 2017 Apr 27. Pharmacol Ther. 2017. PMID: 28457804 Review.

2

Histamine receptors: subclasses and specific ligands.

Haaksma EE, Leurs R, Timmerman H. Haaksma EE, et al. Among authors: leurs r. Pharmacol Ther. 1990;47(1):73-104. doi: 10.1016/0163-7258(90)90046-5. Pharmacol Ther. 1990. PMID: 2195558 Review.

3

Molecular pharmacological aspects of histamine receptors.

Leurs R, Smit MJ, Timmerman H. Leurs R, et al. Pharmacol Ther. 1995 Jun;66(3):413-63. doi: 10.1016/0163-7258(95)00006-3. Pharmacol Ther. 1995. PMID: 7494855 Review.

4

Constitutive activity of histamine h(3) receptors stably expressed in SK-N-MC cells: display of agonism and inverse agonism by H(3) antagonists.

Wieland K, Bongers G, Yamamoto Y, Hashimoto T, Yamatodani A, Menge WM, Timmerman H, Lovenberg TW, Leurs R. Wieland K, et al. Among authors: leurs r. J Pharmacol Exp Ther. 2001 Dec;299(3):908-14. J Pharmacol Exp Ther. 2001. PMID: 11714875

5

Improgan antinociception does not require neuronal histamine or histamine receptors.

Izadi Mobarakeh J, Nalwalk JW, Watanabe T, Sakurada S, Hoffman M, Leurs R, Timmerman H, Silos-Santiago I, Yanai K, Hough LB. Izadi Mobarakeh J, et al. Among authors: leurs r. Brain Res. 2003 Jun 6;974(1-2):146-52. doi: 10.1016/s0006-8993(03)02572-1. Brain Res. 2003. PMID: 12742632

6

Effect of the histamine H3-antagonist clobenpropit on spatial memory deficits induced by MK-801 as evaluated by radial maze in Sprague-Dawley rats.

Huang YW, Hu WW, Chen Z, Zhang LS, Shen HQ, Timmerman H, Leurs R, Yanai K. Huang YW, et al. Among authors: leurs r. Behav Brain Res. 2004 May 5;151(1-2):287-93. doi: 10.1016/j.bbr.2003.09.002. Behav Brain Res. 2004. PMID: 15084444

7

Domain swapping in the human histamine H1 receptor.

Bakker RA, Dees G, Carrillo JJ, Booth RG, López-Gimenez JF, Milligan G, Strange PG, Leurs R. Bakker RA, et al. Among authors: leurs r. J Pharmacol Exp Ther. 2004 Oct;311(1):131-8. doi: 10.1124/jpet.104.067041. Epub 2004 May 24. J Pharmacol Exp Ther. 2004. PMID: 15159444

8

Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist.

Lim HD, van Rijn RM, Ling P, Bakker RA, Thurmond RL, Leurs R. Lim HD, et al. Among authors: leurs r. J Pharmacol Exp Ther. 2005 Sep;314(3):1310-21. doi: 10.1124/jpet.105.087965. Epub 2005 Jun 9. J Pharmacol Exp Ther. 2005. PMID: 15947036

9

In vitro pharmacology of clinically used central nervous system-active drugs as inverse H(1) receptor agonists.

Bakker RA, Nicholas MW, Smith TT, Burstein ES, Hacksell U, Timmerman H, Leurs R, Brann MR, Weiner DM. Bakker RA, et al. Among authors: leurs r. J Pharmacol Exp Ther. 2007 Jul;322(1):172-9. doi: 10.1124/jpet.106.118869. Epub 2007 Apr 2. J Pharmacol Exp Ther. 2007. PMID: 17403993

10

Noncompetitive antagonism and inverse agonism as mechanism of action of nonpeptidergic antagonists at primate and rodent CXCR3 chemokine receptors.

Verzijl D, Storelli S, Scholten DJ, Bosch L, Reinhart TA, Streblow DN, Tensen CP, Fitzsimons CP, Zaman GJ, Pease JE, de Esch IJ, Smit MJ, Leurs R. Verzijl D, et al. Among authors: leurs r. J Pharmacol Exp Ther. 2008 May;325(2):544-55. doi: 10.1124/jpet.107.134783. Epub 2008 Feb 12. J Pharmacol Exp Ther. 2008. PMID: 18270317 Free PMC article.

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