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UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma.
Kostyrko K, Román M, Lee AG, Simpson DR, Dinh PT, Leung SG, Marini KD, Kelly MR, Broyde J, Califano A, Jackson PK, Sweet-Cordero EA. Kostyrko K, et al. Among authors: leung sg. Nat Commun. 2023 Jul 5;14(1):3966. doi: 10.1038/s41467-023-39591-2. Nat Commun. 2023. PMID: 37407562 Free PMC article.
Genome-Informed Targeted Therapy for Osteosarcoma.
Sayles LC, Breese MR, Koehne AL, Leung SG, Lee AG, Liu HY, Spillinger A, Shah AT, Tanasa B, Straessler K, Hazard FK, Spunt SL, Marina N, Kim GE, Cho SJ, Avedian RS, Mohler DG, Kim MO, DuBois SG, Hawkins DS, Sweet-Cordero EA. Sayles LC, et al. Among authors: leung sg. Cancer Discov. 2019 Jan;9(1):46-63. doi: 10.1158/2159-8290.CD-17-1152. Epub 2018 Sep 28. Cancer Discov. 2019. PMID: 30266815 Free PMC article.
Antitumor activity of an engineered decoy receptor targeting CLCF1-CNTFR signaling in lung adenocarcinoma.
Kim JW, Marquez CP, Kostyrko K, Koehne AL, Marini K, Simpson DR, Lee AG, Leung SG, Sayles LC, Shrager J, Ferrer I, Paz-Ares L, Gephart MH, Vicent S, Cochran JR, Sweet-Cordero EA. Kim JW, et al. Among authors: leung sg. Nat Med. 2019 Nov;25(11):1783-1795. doi: 10.1038/s41591-019-0612-2. Epub 2019 Nov 7. Nat Med. 2019. PMID: 31700175 Free PMC article.
Hydra: A mixture modeling framework for subtyping pediatric cancer cohorts using multimodal gene expression signatures.
Pfeil J, Sanders LM, Anastopoulos I, Lyle AG, Weinstein AS, Xue Y, Blair A, Beale HC, Lee A, Leung SG, Dinh PT, Shah AT, Breese MR, Devine WP, Bjork I, Salama SR, Sweet-Cordero EA, Haussler D, Vaske OM. Pfeil J, et al. Among authors: leung sg. PLoS Comput Biol. 2020 Apr 10;16(4):e1007753. doi: 10.1371/journal.pcbi.1007753. eCollection 2020 Apr. PLoS Comput Biol. 2020. PMID: 32275708 Free PMC article.
NUP98-NSD1 Driven MDS/MPN in Childhood Masquerading as JMML.
Behnert A, Lee AG, Young EP, Breese MR, Leung SG, Behroozfard I, Maruffi M, Sweet-Cordero EA, Dvorak CC, Chu J, Stieglitz E. Behnert A, et al. Among authors: leung sg. J Pediatr Hematol Oncol. 2021 Aug 1;43(6):e808-e811. doi: 10.1097/MPH.0000000000001913. J Pediatr Hematol Oncol. 2021. PMID: 32815876 Free PMC article.
Development and characterization of new patient-derived xenograft (PDX) models of osteosarcoma with distinct metastatic capacities.
Schott CR, Koehne AL, Sayles LC, Young EP, Luck C, Yu K, Lee AG, Breese MR, Leung SG, Xu H, Shah AT, Liu HY, Spillinger A, Behroozfard IH, Marini KD, Dinh PT, Pons Ventura MAV, Vanderboon EN, Hazard FK, Cho SJ, Avedian RS, Mohler DG, Zimel M, Wustrack R, Curtis C, Sirota M, Sweet-Cordero EA. Schott CR, et al. Among authors: leung sg. bioRxiv [Preprint]. 2023 Jan 20:2023.01.19.524562. doi: 10.1101/2023.01.19.524562. bioRxiv. 2023. PMID: 36711882 Free PMC article. Updated. Preprint.
Osteosarcoma PDX-Derived Cell Line Models for Preclinical Drug Evaluation Demonstrate Metastasis Inhibition by Dinaciclib through a Genome-Targeted Approach.
Schott CR, Koehne AL, Sayles LC, Young EP, Luck C, Yu K, Lee AG, Breese MR, Leung SG, Xu H, Shah AT, Liu HY, Spillinger A, Behroozfard IH, Marini KD, Dinh PT, Pons Ventura MV, Vanderboon EN, Hazard FK, Cho SJ, Avedian RS, Mohler DG, Zimel M, Wustrack R, Curtis C, Sirota M, Sweet-Cordero EA. Schott CR, et al. Among authors: leung sg. Clin Cancer Res. 2024 Feb 16;30(4):849-864. doi: 10.1158/1078-0432.CCR-23-0873. Clin Cancer Res. 2024. PMID: 37703185 Free PMC article.
Pre-and post-HSCT use of TKI therapy for fusion-driven B-ALL: A case series of five pediatric, adolescent and young adult patients.
Shumock SS, Temple WC, Marinoff A, Aaronson K, Southworth E, Xirenayi S, Lee AG, Leung SG, Sweet-Cordero EA, Hermiston M, Higham C, Stieglitz E. Shumock SS, et al. Among authors: leung sg. Cancer Rep (Hoboken). 2023 Dec;6(12):e1901. doi: 10.1002/cnr2.1901. Epub 2023 Nov 7. Cancer Rep (Hoboken). 2023. PMID: 37933765 Free PMC article.
26 results