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Page 1
Discovery, Function, and Therapeutic Targeting of Siglec-8.
Youngblood BA, Leung J, Falahati R, Williams J, Schanin J, Brock EC, Singh B, Chang AT, O'Sullivan JA, Schleimer RP, Tomasevic N, Bebbington CR, Bochner BS. Youngblood BA, et al. Among authors: leung j. Cells. 2020 Dec 24;10(1):19. doi: 10.3390/cells10010019. Cells. 2020. PMID: 33374255 Free PMC article. Review.
The eosinophil surface receptor epidermal growth factor-like module containing mucin-like hormone receptor 1 (EMR1): a novel therapeutic target for eosinophilic disorders.
Legrand F, Tomasevic N, Simakova O, Lee CC, Wang Z, Raffeld M, Makiya MA, Palath V, Leung J, Baer M, Yarranton G, Maric I, Bebbington C, Klion AD. Legrand F, et al. Among authors: leung j. J Allergy Clin Immunol. 2014 May;133(5):1439-47, 1447.e1-8. doi: 10.1016/j.jaci.2013.11.041. Epub 2014 Feb 13. J Allergy Clin Immunol. 2014. PMID: 24530099 Free PMC article. Clinical Trial.
Anti-Siglec-8 Antibody for Eosinophilic Gastritis and Duodenitis.
Dellon ES, Peterson KA, Murray JA, Falk GW, Gonsalves N, Chehade M, Genta RM, Leung J, Khoury P, Klion AD, Hazan S, Vaezi M, Bledsoe AC, Durrani SR, Wang C, Shaw C, Chang AT, Singh B, Kamboj AP, Rasmussen HS, Rothenberg ME, Hirano I. Dellon ES, et al. Among authors: leung j. N Engl J Med. 2020 Oct 22;383(17):1624-1634. doi: 10.1056/NEJMoa2012047. N Engl J Med. 2020. PMID: 33085861 Free PMC article. Clinical Trial.
Mast Cell and Eosinophil Activation Are Associated With COVID-19 and TLR-Mediated Viral Inflammation: Implications for an Anti-Siglec-8 Antibody.
Gebremeskel S, Schanin J, Coyle KM, Butuci M, Luu T, Brock EC, Xu A, Wong A, Leung J, Korver W, Morin RD, Schleimer RP, Bochner BS, Youngblood BA. Gebremeskel S, et al. Among authors: leung j. Front Immunol. 2021 Mar 10;12:650331. doi: 10.3389/fimmu.2021.650331. eCollection 2021. Front Immunol. 2021. PMID: 33777047 Free PMC article.
Functional and Phenotypic Characterization of Siglec-6 on Human Mast Cells.
Robida PA, Rische CH, Morgenstern NB, Janarthanam R, Cao Y, Krier-Burris RA, Korver W, Xu A, Luu T, Schanin J, Leung J, Rothenberg ME, Wechsler JB, Youngblood BA, Bochner BS, O'Sullivan JA. Robida PA, et al. Among authors: leung j. Cells. 2022 Mar 28;11(7):1138. doi: 10.3390/cells11071138. Cells. 2022. PMID: 35406705 Free PMC article.
Development of a core outcome set for therapeutic studies in eosinophilic esophagitis (COREOS).
COREOS Collaborators:; Ma C, Schoepfer AM, Dellon ES, Bredenoord AJ, Chehade M, Collins MH, Feagan BG, Furuta GT, Gupta SK, Hirano I, Jairath V, Katzka DA, Pai RK, Rothenberg ME, Straumann A, Aceves SS, Alexander JA, Arva NC, Atkins D, Biedermann L, Blanchard C, Cianferoni A, Ciriza de Los Rios C, Clayton F, Davis CM, de Bortoli N, Dias JA, Falk GW, Genta RM, Ghaffari G, Gonsalves N, Greuter T, Hopp R, Hsu Blatman KS, Jensen ET, Johnston D, Kagalwalla AF, Larsson HM, Leung J, Louis H, Masterson JC, Menard-Katcher C, Menard-Katcher PA, Moawad FJ, Muir AB, Mukkada VA, Penagini R, Pesek RD, Peterson K, Putnam PE, Ravelli A, Savarino EV, Schlag C, Schreiner P, Simon D, Smyrk TC, Spergel JM, Taft TH, Terreehorst I, Vanuytsel T, Venter C, Vieira MC, Vieth M, Vlieg-Boerstra B, von Arnim U, Walker MM, Wechsler JB, Woodland P, Woosley JT, Yang GY, Zevit N, Safroneeva E. COREOS Collaborators:, et al. Among authors: leung j. J Allergy Clin Immunol. 2022 Feb;149(2):659-670. doi: 10.1016/j.jaci.2021.07.001. Epub 2021 Jul 6. J Allergy Clin Immunol. 2022. PMID: 34242635 Free PMC article.
Identification of human CCR8 as a CCL18 receptor.
Islam SA, Ling MF, Leung J, Shreffler WG, Luster AD. Islam SA, et al. Among authors: leung j. J Exp Med. 2013 Sep 23;210(10):1889-98. doi: 10.1084/jem.20130240. Epub 2013 Sep 2. J Exp Med. 2013. PMID: 23999500 Free PMC article.
Esophageal type 2 cytokine expression heterogeneity in eosinophilic esophagitis in a multisite cohort.
Dunn JLM, Shoda T, Caldwell JM, Wen T, Aceves SS, Collins MH, Dellon ES, Falk GW, Leung J, Martin LJ, Menard-Katcher P, Rudman-Spergel AK, Spergel JM, Wechsler JB, Yang GY, Furuta GT, Rothenberg ME; Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR). Dunn JLM, et al. Among authors: leung j. J Allergy Clin Immunol. 2020 Jun;145(6):1629-1640.e4. doi: 10.1016/j.jaci.2020.01.051. Epub 2020 Mar 19. J Allergy Clin Immunol. 2020. PMID: 32197970 Free PMC article.
Evaluating Eosinophilic Colitis as a Unique Disease Using Colonic Molecular Profiles: A Multi-Site Study.
Shoda T, Collins MH, Rochman M, Wen T, Caldwell JM, Mack LE, Osswald GA, Besse JA, Haberman Y, Aceves SS, Arva NC, Capocelli KE, Chehade M, Davis CM, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Hirano I, Khoury P, Klion A, Menard-Katcher C, Leung J, Mukkada VA, Putnam PE, Spergel JM, Wechsler JB, Yang GY, Furuta GT, Denson LA, Rothenberg ME; Consortium of Eosinophilic Gastrointestinal Diseases Researchers (CEGIR). Shoda T, et al. Among authors: leung j. Gastroenterology. 2022 May;162(6):1635-1649. doi: 10.1053/j.gastro.2022.01.022. Epub 2022 Jan 25. Gastroenterology. 2022. PMID: 35085569 Free PMC article.
2,717 results