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A monoclonal antibody to Siglec-8 suppresses non-allergic airway inflammation and inhibits IgE-independent mast cell activation.
Schanin J, Gebremeskel S, Korver W, Falahati R, Butuci M, Haw TJ, Nair PM, Liu G, Hansbro NG, Hansbro PM, Evensen E, Brock EC, Xu A, Wong A, Leung J, Bebbington C, Tomasevic N, Youngblood BA. Schanin J, et al. Among authors: leung j. Mucosal Immunol. 2021 Mar;14(2):366-376. doi: 10.1038/s41385-020-00336-9. Epub 2020 Aug 19. Mucosal Immunol. 2021. PMID: 32814824 Free PMC article.
The first propeller domain of LRP6 regulates sensitivity to DKK1.
Binnerts ME, Tomasevic N, Bright JM, Leung J, Ahn VE, Kim KA, Zhan X, Liu S, Yonkovich S, Williams J, Zhou M, Gros D, Dixon M, Korver W, Weis WI, Abo A. Binnerts ME, et al. Among authors: leung j. Mol Biol Cell. 2009 Aug;20(15):3552-60. doi: 10.1091/mbc.e08-12-1252. Epub 2009 May 28. Mol Biol Cell. 2009. PMID: 19477926 Free PMC article.
AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice.
Youngblood BA, Brock EC, Leung J, Falahati R, Bryce PJ, Bright J, Williams J, Shultz LD, Greiner DL, Brehm MA, Bebbington C, Tomasevic N. Youngblood BA, et al. Among authors: leung j. Int Arch Allergy Immunol. 2019;180(2):91-102. doi: 10.1159/000501637. Epub 2019 Aug 9. Int Arch Allergy Immunol. 2019. PMID: 31401630 Free PMC article.
R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6.
Binnerts ME, Kim KA, Bright JM, Patel SM, Tran K, Zhou M, Leung JM, Liu Y, Lomas WE 3rd, Dixon M, Hazell SA, Wagle M, Nie WS, Tomasevic N, Williams J, Zhan X, Levy MD, Funk WD, Abo A. Binnerts ME, et al. Among authors: leung jm. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14700-5. doi: 10.1073/pnas.0702305104. Epub 2007 Sep 5. Proc Natl Acad Sci U S A. 2007. PMID: 17804805 Free PMC article.
2,717 results