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Page 1
IL-17A inhibition by secukinumab induces early clinical, histopathologic, and molecular resolution of psoriasis.
Krueger JG, Wharton KA Jr, Schlitt T, Suprun M, Torene RI, Jiang X, Wang CQ, Fuentes-Duculan J, Hartmann N, Peters T, Koroleva I, Hillenbrand R, Letzkus M, Yu X, Li Y, Glueck A, Hasselberg A, Flannery B, Suárez-Fariñas M, Hueber W. Krueger JG, et al. Among authors: letzkus m. J Allergy Clin Immunol. 2019 Sep;144(3):750-763. doi: 10.1016/j.jaci.2019.04.029. Epub 2019 May 24. J Allergy Clin Immunol. 2019. PMID: 31129129 Free article. Clinical Trial.
Omalizumab normalizes the gene expression signature of lesional skin in patients with chronic spontaneous urticaria: A randomized, double-blind, placebo-controlled study.
Metz M, Torene R, Kaiser S, Beste MT, Staubach P, Bauer A, Brehler R, Gericke J, Letzkus M, Hartmann N, Erpenbeck VJ, Maurer M. Metz M, et al. Among authors: letzkus m. Allergy. 2019 Jan;74(1):141-151. doi: 10.1111/all.13547. Epub 2018 Oct 15. Allergy. 2019. PMID: 29974963 Clinical Trial.
Canakinumab reverses overexpression of inflammatory response genes in tumour necrosis factor receptor-associated periodic syndrome.
Torene R, Nirmala N, Obici L, Cattalini M, Tormey V, Caorsi R, Starck-Schwertz S, Letzkus M, Hartmann N, Abrams K, Lachmann H, Gattorno M. Torene R, et al. Among authors: letzkus m. Ann Rheum Dis. 2017 Jan;76(1):303-309. doi: 10.1136/annrheumdis-2016-209335. Epub 2016 Jul 29. Ann Rheum Dis. 2017. PMID: 27474763 Free PMC article. Clinical Trial.
Robust and tissue-independent gender-specific transcript biomarkers.
Staedtler F, Hartmann N, Letzkus M, Bongiovanni S, Scherer A, Marc P, Johnson KJ, Schumacher MM. Staedtler F, et al. Among authors: letzkus m. Biomarkers. 2013 Aug;18(5):436-45. doi: 10.3109/1354750X.2013.811538. Epub 2013 Jul 8. Biomarkers. 2013. PMID: 23829492
The effects of angiotensin receptor neprilysin inhibition by sacubitril/valsartan on adipose tissue transcriptome and protein expression in obese hypertensive patients.
Stinkens R, van der Kolk BW, Jordan J, Jax T, Engeli S, Heise T, Jocken JW, May M, Schindler C, Havekes B, Schaper N, Albrecht D, Kaiser S, Hartmann N, Letzkus M, Langenickel TH, Goossens GH, Blaak EE. Stinkens R, et al. Among authors: letzkus m. Sci Rep. 2018 Mar 2;8(1):3933. doi: 10.1038/s41598-018-22194-z. Sci Rep. 2018. PMID: 29500454 Free PMC article. Clinical Trial.
Gene expression profiling of immunomagnetically separated cells directly from stabilized whole blood for multicenter clinical trials.
Letzkus M, Luesink E, Starck-Schwertz S, Bigaud M, Mirza F, Hartmann N, Gerstmayer B, Janssen U, Scherer A, Schumacher MM, Verles A, Vitaliti A, Nirmala N, Johnson KJ, Staedtler F. Letzkus M, et al. Clin Transl Med. 2014 Nov 13;3:36. doi: 10.1186/s40169-014-0036-z. eCollection 2014. Clin Transl Med. 2014. PMID: 25984272 Free PMC article.
Integrated epigenetics of human breast cancer: synoptic investigation of targeted genes, microRNAs and proteins upon demethylation treatment.
Radpour R, Barekati Z, Kohler C, Schumacher MM, Grussenmeyer T, Jenoe P, Hartmann N, Moes S, Letzkus M, Bitzer J, Lefkovits I, Staedtler F, Zhong XY. Radpour R, et al. Among authors: letzkus m. PLoS One. 2011;6(11):e27355. doi: 10.1371/journal.pone.0027355. Epub 2011 Nov 4. PLoS One. 2011. PMID: 22076154 Free PMC article.
The molecular signature of oxidative metabolism and the mode of macrophage activation determine the shift from acute to chronic disease in experimental arthritis: critical role of interleukin-12p40.
Takahashi N, de Jager VC, Glück A, Letzkus M, Hartmann N, Staedtler F, Ribeiro-Dias F, Heuvelmans-Jacobs M, van den Berg WB, Joosten LA. Takahashi N, et al. Among authors: letzkus m. Arthritis Rheum. 2008 Nov;58(11):3471-84. doi: 10.1002/art.23956. Arthritis Rheum. 2008. PMID: 18975327 Free article.
15 results