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Designed Ankyrin Repeat Proteins provide insights into the structure and function of CagI and are potent inhibitors of CagA translocation by the Helicobacter pylori type IV secretion system.
Blanc M, Lettl C, Guérin J, Vieille A, Furler S, Briand-Schumacher S, Dreier B, Bergé C, Plückthun A, Vadon-Le Goff S, Fronzes R, Rousselle P, Fischer W, Terradot L. Blanc M, et al. Among authors: lettl c. PLoS Pathog. 2023 May 8;19(5):e1011368. doi: 10.1371/journal.ppat.1011368. eCollection 2023 May. PLoS Pathog. 2023. PMID: 37155700 Free PMC article.
Heavy metal sensitivities of gene deletion strains for ITT1 and RPS1A connect their activities to the expression of URE2, a key gene involved in metal detoxification in yeast.
Moteshareie H, Hajikarimlou M, Mulet Indrayanti A, Burnside D, Paula Dias A, Lettl C, Ahmed D, Omidi K, Kazmirchuk T, Puchacz N, Zare N, Takallou S, Naing T, Hernández RB, Willmore WG, Babu M, McKay B, Samanfar B, Holcik M, Golshani A. Moteshareie H, et al. Among authors: lettl c. PLoS One. 2018 Sep 19;13(9):e0198704. doi: 10.1371/journal.pone.0198704. eCollection 2018. PLoS One. 2018. PMID: 30231023 Free PMC article.
Designing anti-Zika virus peptides derived from predicted human-Zika virus protein-protein interactions.
Kazmirchuk T, Dick K, Burnside DJ, Barnes B, Moteshareie H, Hajikarimlou M, Omidi K, Ahmed D, Low A, Lettl C, Hooshyar M, Schoenrock A, Pitre S, Babu M, Cassol E, Samanfar B, Wong A, Dehne F, Green JR, Golshani A. Kazmirchuk T, et al. Among authors: lettl c. Comput Biol Chem. 2017 Dec;71:180-187. doi: 10.1016/j.compbiolchem.2017.10.011. Epub 2017 Nov 2. Comput Biol Chem. 2017. PMID: 29112936