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ENDOGLIN is dispensable for vasculogenesis, but required for vascular endothelial growth factor-induced angiogenesis.
Liu Z, Lebrin F, Maring JA, van den Driesche S, van der Brink S, van Dinther M, Thorikay M, Martin S, Kobayashi K, Hawinkels LJ, van Meeteren LA, Pardali E, Korving J, Letarte M, Arthur HM, Theuer C, Goumans MJ, Mummery C, ten Dijke P. Liu Z, et al. Among authors: letarte m. PLoS One. 2014 Jan 28;9(1):e86273. doi: 10.1371/journal.pone.0086273. eCollection 2014. PLoS One. 2014. PMID: 24489709 Free PMC article.
Endoglin null endothelial cells proliferate faster and are more responsive to transforming growth factor beta1 with higher affinity receptors and an activated Alk1 pathway.
Pece-Barbara N, Vera S, Kathirkamathamby K, Liebner S, Di Guglielmo GM, Dejana E, Wrana JL, Letarte M. Pece-Barbara N, et al. Among authors: letarte m. J Biol Chem. 2005 Jul 29;280(30):27800-8. doi: 10.1074/jbc.M503471200. Epub 2005 May 27. J Biol Chem. 2005. PMID: 15923183 Free article.
182 results