Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

25 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology.
Hammam K, Saez-Ayala M, Rebuffet E, Gros L, Lopez S, Hajem B, Humbert M, Baudelet E, Audebert S, Betzi S, Lugari A, Combes S, Letard S, Casteran N, Mansfield C, Moussy A, De Sepulveda P, Morelli X, Dubreuil P. Hammam K, et al. Among authors: letard s. Nat Commun. 2017 Nov 10;8(1):1420. doi: 10.1038/s41467-017-01582-5. Nat Commun. 2017. PMID: 29127277 Free PMC article.
Masitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting KIT.
Dubreuil P, Letard S, Ciufolini M, Gros L, Humbert M, Castéran N, Borge L, Hajem B, Lermet A, Sippl W, Voisset E, Arock M, Auclair C, Leventhal PS, Mansfield CD, Moussy A, Hermine O. Dubreuil P, et al. Among authors: letard s. PLoS One. 2009 Sep 30;4(9):e7258. doi: 10.1371/journal.pone.0007258. PLoS One. 2009. PMID: 19789626 Free PMC article.
Signal transduction by several KIT juxtamembrane domain mutations.
Casteran N, De Sepulveda P, Beslu N, Aoubala M, Letard S, Lecocq E, Rottapel R, Dubreuil P. Casteran N, et al. Among authors: letard s. Oncogene. 2003 Jul 24;22(30):4710-22. doi: 10.1038/sj.onc.1206587. Oncogene. 2003. PMID: 12879016
Mast cell leukemia: identification of a new c-Kit mutation, dup(501-502), and response to masitinib, a c-Kit tyrosine kinase inhibitor.
Georgin-Lavialle S, Lhermitte L, Suarez F, Yang Y, Letard S, Hanssens K, Feger F, Renand A, Brouze C, Canioni D, Asnafi V, Chandesris MO, Aouba A, Gineste P, Macintyre E, Mansfield CD, Moussy A, Lepelletier Y, Dubreuil P, Hermine O. Georgin-Lavialle S, et al. Among authors: letard s. Eur J Haematol. 2012 Jul;89(1):47-52. doi: 10.1111/j.1600-0609.2012.01761.x. Epub 2012 Apr 28. Eur J Haematol. 2012. PMID: 22324351
Pediatric mastocytosis-associated KIT extracellular domain mutations exhibit different functional and signaling properties compared with KIT-phosphotransferase domain mutations.
Yang Y, Létard S, Borge L, Chaix A, Hanssens K, Lopez S, Vita M, Finetti P, Birnbaum D, Bertucci F, Gomez S, de Sepulveda P, Dubreuil P. Yang Y, et al. Among authors: letard s. Blood. 2010 Aug 19;116(7):1114-23. doi: 10.1182/blood-2009-06-226027. Epub 2010 May 18. Blood. 2010. PMID: 20484085 Free article.
Dual Role of the Tyrosine Kinase Syk in Regulation of Toll-Like Receptor Signaling in Plasmacytoid Dendritic Cells.
Aouar B, Kovarova D, Letard S, Font-Haro A, Florentin J, Weber J, Durantel D, Chaperot L, Plumas J, Trejbalova K, Hejnar J, Nunès JA, Olive D, Dubreuil P, Hirsch I, Stranska R. Aouar B, et al. Among authors: letard s. PLoS One. 2016 Jun 3;11(6):e0156063. doi: 10.1371/journal.pone.0156063. eCollection 2016. PLoS One. 2016. PMID: 27258042 Free PMC article.
25 results