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Combined EZH2 and Bcl-2 inhibitors as precision therapy for genetically defined DLBCL subtypes.
Scholze H, Stephenson RE, Reynolds R, Shah S, Puri R, Butler SD, Trujillo-Alonso V, Teater MR, van Besien H, Gibbs-Curtis D, Ueno H, Parvin S, Letai A, Mathew S, Singh A, Cesarman E, Melnick A, Giulino-Roth L. Scholze H, et al. Among authors: letai a. Blood Adv. 2020 Oct 27;4(20):5226-5231. doi: 10.1182/bloodadvances.2020002580. Blood Adv. 2020. PMID: 33104794 Free PMC article.
BCL-2: found bound and drugged!
Letai A. Letai A. Trends Mol Med. 2005 Oct;11(10):442-4. doi: 10.1016/j.molmed.2005.08.007. Trends Mol Med. 2005. PMID: 16150641 Review.
BH3-only proteins and their effects on cancer.
Vo TT, Letai A. Vo TT, et al. Among authors: letai a. Adv Exp Med Biol. 2010;687:49-63. doi: 10.1007/978-1-4419-6706-0_3. Adv Exp Med Biol. 2010. PMID: 20919637 Free PMC article. Review.
A new face of BCL-2 inhibition in CLL.
Letai A. Letai A. Blood. 2011 Mar 10;117(10):2750-1. doi: 10.1182/blood-2011-01-328658. Blood. 2011. PMID: 21393499 Free article. No abstract available.
Targeting Bcl-2 in CLL: cui bono?
Letai A. Letai A. Blood. 2011 Sep 29;118(13):3453-4. doi: 10.1182/blood-2011-08-370346. Blood. 2011. PMID: 21960677 Free article. No abstract available.
BCL2 suppresses PARP1 function and nonapoptotic cell death.
Dutta C, Day T, Kopp N, van Bodegom D, Davids MS, Ryan J, Bird L, Kommajosyula N, Weigert O, Yoda A, Fung H, Brown JR, Shapiro GI, Letai A, Weinstock DM. Dutta C, et al. Among authors: letai a. Cancer Res. 2012 Aug 15;72(16):4193-203. doi: 10.1158/0008-5472.CAN-11-4204. Epub 2012 Jun 11. Cancer Res. 2012. PMID: 22689920 Free PMC article.
211 results