Lesné S - Search Results

1

Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer's Disease, Parkinson's Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis.

Nguyen PH, Ramamoorthy A, Sahoo BR, Zheng J, Faller P, Straub JE, Dominguez L, Shea JE, Dokholyan NV, De Simone A, Ma B, Nussinov R, Najafi S, Ngo ST, Loquet A, Chiricotto M, Ganguly P, McCarty J, Li MS, Hall C, Wang Y, Miller Y, Melchionna S, Habenstein B, Timr S, Chen J, Hnath B, Strodel B, Kayed R, Lesné S, Wei G, Sterpone F, Doig AJ, Derreumaux P. Nguyen PH, et al. Among authors: lesne s. Chem Rev. 2021 Feb 24;121(4):2545-2647. doi: 10.1021/acs.chemrev.0c01122. Epub 2021 Feb 5. Chem Rev. 2021. PMID: 33543942 Free PMC article. Review.

2

A specific amyloid-beta protein assembly in the brain impairs memory.

Lesné S, Koh MT, Kotilinek L, Kayed R, Glabe CG, Yang A, Gallagher M, Ashe KH. Lesné S, et al. Nature. 2006 Mar 16;440(7082):352-7. doi: 10.1038/nature04533. Nature. 2006. PMID: 16541076

3

Brain amyloid-β oligomers in ageing and Alzheimer's disease.

Lesné SE, Sherman MA, Grant M, Kuskowski M, Schneider JA, Bennett DA, Ashe KH. Lesné SE, et al. Brain. 2013 May;136(Pt 5):1383-98. doi: 10.1093/brain/awt062. Epub 2013 Apr 9. Brain. 2013. PMID: 23576130 Free PMC article.

4

Selective lowering of synapsins induced by oligomeric α-synuclein exacerbates memory deficits.

Larson ME, Greimel SJ, Amar F, LaCroix M, Boyle G, Sherman MA, Schley H, Miel C, Schneider JA, Kayed R, Benfenati F, Lee MK, Bennett DA, Lesné SE. Larson ME, et al. Among authors: lesne se. Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):E4648-E4657. doi: 10.1073/pnas.1704698114. Epub 2017 May 22. Proc Natl Acad Sci U S A. 2017. PMID: 28533388 Free PMC article.

5

Soluble endogenous oligomeric α-synuclein species in neurodegenerative diseases: Expression, spreading, and cross-talk.

Kayed R, Dettmer U, Lesné SE. Kayed R, et al. Among authors: lesne se. J Parkinsons Dis. 2020;10(3):791-818. doi: 10.3233/JPD-201965. J Parkinsons Dis. 2020. PMID: 32508330 Free PMC article. Review.

6

Detecting aβ*56 oligomers in brain tissues.

Sherman MA, Lesné SE. Sherman MA, et al. Methods Mol Biol. 2011;670:45-56. doi: 10.1007/978-1-60761-744-0_4. Methods Mol Biol. 2011. PMID: 20967582

7

Soluble α-synuclein is a novel modulator of Alzheimer's disease pathophysiology.

Larson ME, Sherman MA, Greimel S, Kuskowski M, Schneider JA, Bennett DA, Lesné SE. Larson ME, et al. Among authors: lesne se. J Neurosci. 2012 Jul 25;32(30):10253-66. doi: 10.1523/JNEUROSCI.0581-12.2012. J Neurosci. 2012. PMID: 22836259 Free PMC article.

8

The complex PrP(c)-Fyn couples human oligomeric Aβ with pathological tau changes in Alzheimer's disease.

Larson M, Sherman MA, Amar F, Nuvolone M, Schneider JA, Bennett DA, Aguzzi A, Lesné SE. Larson M, et al. J Neurosci. 2012 Nov 21;32(47):16857-71a. doi: 10.1523/JNEUROSCI.1858-12.2012. J Neurosci. 2012. PMID: 23175838 Free PMC article.

9

Toxic oligomer species of amyloid-β in Alzheimer's disease, a timing issue.

Lesne SE. Lesne SE. Swiss Med Wkly. 2014 Nov 6;144:w14021. doi: 10.4414/smw.2014.14021. eCollection 2014. Swiss Med Wkly. 2014. PMID: 25375761 Free PMC article. Review.

10

Discrete Pools of Oligomeric Amyloid-β Track with Spatial Learning Deficits in a Mouse Model of Alzheimer Amyloidosis.

Chiang ACA, Fowler SW, Reddy R, Pletnikova O, Troncoso JC, Sherman MA, Lesne SE, Jankowsky JL. Chiang ACA, et al. Among authors: lesne se. Am J Pathol. 2018 Mar;188(3):739-756. doi: 10.1016/j.ajpath.2017.11.011. Epub 2017 Dec 15. Am J Pathol. 2018. PMID: 29248459 Free PMC article.

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