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c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis.
Leslie J, Macia MG, Luli S, Worrell JC, Reilly WJ, Paish HL, Knox A, Barksby BS, Gee LM, Zaki MYW, Collins AL, Burgoyne RA, Cameron R, Bragg C, Xu X, Chung GW, Brown CDA, Blanchard AD, Nanthakumar CB, Karsdal M, Robinson SM, Manas DM, Sen G, French J, White SA, Murphy S, Trost M, Zakrzewski JL, Klein U, Schwabe RF, Mederacke I, Nixon C, Bird T, Teuwen LA, Schoonjans L, Carmeliet P, Mann J, Fisher AJ, Sheerin NS, Borthwick LA, Mann DA, Oakley F. Leslie J, et al. Nat Metab. 2020 Nov;2(11):1350-1367. doi: 10.1038/s42255-020-00306-2. Epub 2020 Nov 9. Nat Metab. 2020. PMID: 33168981 Free PMC article.
A Proof-of-Concept for Epigenetic Therapy of Tissue Fibrosis: Inhibition of Liver Fibrosis Progression by 3-Deazaneplanocin A.
Zeybel M, Luli S, Sabater L, Hardy T, Oakley F, Leslie J, Page A, Moran Salvador E, Sharkey V, Tsukamoto H, Chu DCK, Singh US, Ponzoni M, Perri P, Di Paolo D, Mendivil EJ, Mann J, Mann DA. Zeybel M, et al. Among authors: leslie j. Mol Ther. 2017 Jan 4;25(1):218-231. doi: 10.1016/j.ymthe.2016.10.004. Epub 2017 Jan 4. Mol Ther. 2017. PMID: 28129116 Free PMC article.
A Bioreactor Technology for Modeling Fibrosis in Human and Rodent Precision-Cut Liver Slices.
Paish HL, Reed LH, Brown H, Bryan MC, Govaere O, Leslie J, Barksby BS, Garcia Macia M, Watson A, Xu X, Zaki MYW, Greaves L, Whitehall J, French J, White SA, Manas DM, Robinson SM, Spoletini G, Griffiths C, Mann DA, Borthwick LA, Drinnan MJ, Mann J, Oakley F. Paish HL, et al. Among authors: leslie j. Hepatology. 2019 Oct;70(4):1377-1391. doi: 10.1002/hep.30651. Epub 2019 May 28. Hepatology. 2019. PMID: 30963615 Free PMC article.
Ammonia Scavenging Prevents Progression of Fibrosis in Experimental Nonalcoholic Fatty Liver Disease.
De Chiara F, Thomsen KL, Habtesion A, Jones H, Davies N, Gracia-Sancho J, Manicardi N, Hall A, Andreola F, Paish HL, Reed LH, Watson AA, Leslie J, Oakley F, Rombouts K, Mookerjee RP, Mann J, Jalan R. De Chiara F, et al. Among authors: leslie j. Hepatology. 2020 Mar;71(3):874-892. doi: 10.1002/hep.30890. Epub 2019 Oct 15. Hepatology. 2020. PMID: 31378982
598 results