Leslie EM - Search Results

1

Transporters and Toxicity: Insights From the International Transporter Consortium Workshop 4.

Hafey MJ, Aleksunes LM, Bridges CC, Brouwer KR, Chien HC, Leslie EM, Hu S, Li Y, Shen J, Sparreboom A, Sprowl J, Tweedie D, Lai Y. Hafey MJ, et al. Among authors: leslie em. Clin Pharmacol Ther. 2022 Sep;112(3):527-539. doi: 10.1002/cpt.2638. Epub 2022 Jun 10. Clin Pharmacol Ther. 2022. PMID: 35546260 Review.

2

Differential inhibition of rat and human Na+-dependent taurocholate cotransporting polypeptide (NTCP/SLC10A1)by bosentan: a mechanism for species differences in hepatotoxicity.

Leslie EM, Watkins PB, Kim RB, Brouwer KL. Leslie EM, et al. J Pharmacol Exp Ther. 2007 Jun;321(3):1170-8. doi: 10.1124/jpet.106.119073. Epub 2007 Mar 20. J Pharmacol Exp Ther. 2007. PMID: 17374746

3

A novel pathway for arsenic elimination: human multidrug resistance protein 4 (MRP4/ABCC4) mediates cellular export of dimethylarsinic acid (DMAV) and the diglutathione conjugate of monomethylarsonous acid (MMAIII).

Banerjee M, Carew MW, Roggenbeck BA, Whitlock BD, Naranmandura H, Le XC, Leslie EM. Banerjee M, et al. Among authors: leslie em. Mol Pharmacol. 2014 Aug;86(2):168-79. doi: 10.1124/mol.113.091314. Epub 2014 May 28. Mol Pharmacol. 2014. PMID: 24870404

4

Arsenic Triglutathione [As(GS)3] Transport by Multidrug Resistance Protein 1 (MRP1/ABCC1) Is Selectively Modified by Phosphorylation of Tyr920/Ser921 and Glycosylation of Asn19/Asn23.

Shukalek CB, Swanlund DP, Rousseau RK, Weigl KE, Marensi V, Cole SP, Leslie EM. Shukalek CB, et al. Among authors: leslie em. Mol Pharmacol. 2016 Aug;90(2):127-39. doi: 10.1124/mol.116.103648. Epub 2016 Jun 13. Mol Pharmacol. 2016. PMID: 27297967

5

Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense.

Leslie EM, Deeley RG, Cole SP. Leslie EM, et al. Toxicol Appl Pharmacol. 2005 May 1;204(3):216-37. doi: 10.1016/j.taap.2004.10.012. Toxicol Appl Pharmacol. 2005. PMID: 15845415 Review.

6

In vitro-in vivo correlation of hepatobiliary drug clearance in humans.

Ghibellini G, Vasist LS, Leslie EM, Heizer WD, Kowalsky RJ, Calvo BF, Brouwer KL. Ghibellini G, et al. Among authors: leslie em. Clin Pharmacol Ther. 2007 Mar;81(3):406-13. doi: 10.1038/sj.clpt.6100059. Epub 2007 Jan 18. Clin Pharmacol Ther. 2007. PMID: 17235333

7

Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and atpase activities by interaction with dietary flavonoids.

Leslie EM, Mao Q, Oleschuk CJ, Deeley RG, Cole SP. Leslie EM, et al. Mol Pharmacol. 2001 May;59(5):1171-80. doi: 10.1124/mol.59.5.1171. Mol Pharmacol. 2001. PMID: 11306701

8

Human red blood cell uptake and sequestration of arsenite and selenite: Evidence of seleno-bis(S-glutathionyl) arsinium ion formation in human cells.

Kaur G, Javed W, Ponomarenko O, Shekh K, Swanlund DP, Zhou JR, Summers KL, Casini A, Wenzel MN, Casey JR, Cordat E, Pickering IJ, George GN, Leslie EM. Kaur G, et al. Among authors: leslie em. Biochem Pharmacol. 2020 Oct;180:114141. doi: 10.1016/j.bcp.2020.114141. Epub 2020 Jul 8. Biochem Pharmacol. 2020. PMID: 32652143

9

Polymorphic variants of MRP4/ABCC4 differentially modulate the transport of methylated arsenic metabolites and physiological organic anions.

Banerjee M, Marensi V, Conseil G, Le XC, Cole SP, Leslie EM. Banerjee M, et al. Among authors: leslie em. Biochem Pharmacol. 2016 Nov 15;120:72-82. doi: 10.1016/j.bcp.2016.09.016. Epub 2016 Sep 19. Biochem Pharmacol. 2016. PMID: 27659809

10

Cellular arsenic transport pathways in mammals.

Roggenbeck BA, Banerjee M, Leslie EM. Roggenbeck BA, et al. Among authors: leslie em. J Environ Sci (China). 2016 Nov;49:38-58. doi: 10.1016/j.jes.2016.10.001. Epub 2016 Oct 29. J Environ Sci (China). 2016. PMID: 28007179 Review.

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