Lesina M - Search Results

1

Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase.

Ruess DA, Heynen GJ, Ciecielski KJ, Ai J, Berninger A, Kabacaoglu D, Görgülü K, Dantes Z, Wörmann SM, Diakopoulos KN, Karpathaki AF, Kowalska M, Kaya-Aksoy E, Song L, van der Laan EAZ, López-Alberca MP, Nazaré M, Reichert M, Saur D, Erkan MM, Hopt UT, Sainz B Jr, Birchmeier W, Schmid RM, Lesina M, Algül H. Ruess DA, et al. Among authors: lesina m. Nat Med. 2018 Jul;24(7):954-960. doi: 10.1038/s41591-018-0024-8. Epub 2018 May 28. Nat Med. 2018. PMID: 29808009 Free article.

2

Pancreas-specific RelA/p65 truncation increases susceptibility of acini to inflammation-associated cell death following cerulein pancreatitis.

Algül H, Treiber M, Lesina M, Nakhai H, Saur D, Geisler F, Pfeifer A, Paxian S, Schmid RM. Algül H, et al. Among authors: lesina m. J Clin Invest. 2007 Jun;117(6):1490-501. doi: 10.1172/JCI29882. Epub 2007 May 24. J Clin Invest. 2007. PMID: 17525802 Free PMC article.

3

Overexpression of ErbB2 in the exocrine pancreas induces an inflammatory response but not increased proliferation.

Algül H, Wagner M, Lesina M, Schmid RM. Algül H, et al. Among authors: lesina m. Int J Cancer. 2007 Oct 1;121(7):1410-6. doi: 10.1002/ijc.22779. Int J Cancer. 2007. PMID: 17546589 Free article.

4

Mechanisms of disease: chronic inflammation and cancer in the pancreas--a potential role for pancreatic stellate cells?

Algül H, Treiber M, Lesina M, Schmid RM. Algül H, et al. Among authors: lesina m. Nat Clin Pract Gastroenterol Hepatol. 2007 Aug;4(8):454-62. doi: 10.1038/ncpgasthep0881. Nat Clin Pract Gastroenterol Hepatol. 2007. PMID: 17667994 Review.

5

Betacellulin protects from pancreatitis by activating stress-activated protein kinase.

Dahlhoff M, Algül H, Siveke JT, Lesina M, Wanke R, Wartmann T, Halangk W, Schmid RM, Wolf E, Schneider MR. Dahlhoff M, et al. Among authors: lesina m. Gastroenterology. 2010 Apr;138(4):1585-94, 1594.e1-3. doi: 10.1053/j.gastro.2009.12.045. Epub 2009 Dec 29. Gastroenterology. 2010. PMID: 20038432

6

Stat3/Socs3 activation by IL-6 transsignaling promotes progression of pancreatic intraepithelial neoplasia and development of pancreatic cancer.

Lesina M, Kurkowski MU, Ludes K, Rose-John S, Treiber M, Klöppel G, Yoshimura A, Reindl W, Sipos B, Akira S, Schmid RM, Algül H. Lesina M, et al. Cancer Cell. 2011 Apr 12;19(4):456-69. doi: 10.1016/j.ccr.2011.03.009. Cancer Cell. 2011. PMID: 21481788 Free article.

7

Early requirement of Rac1 in a mouse model of pancreatic cancer.

Heid I, Lubeseder-Martellato C, Sipos B, Mazur PK, Lesina M, Schmid RM, Siveke JT. Heid I, et al. Among authors: lesina m. Gastroenterology. 2011 Aug;141(2):719-30, 730.e1-7. doi: 10.1053/j.gastro.2011.04.043. Epub 2011 Apr 28. Gastroenterology. 2011. PMID: 21684285

8

Myeloid, but not pancreatic, RelA/p65 is required for fibrosis in a mouse model of chronic pancreatitis.

Treiber M, Neuhöfer P, Anetsberger E, Einwächter H, Lesina M, Rickmann M, Liang S, Kehl T, Nakhai H, Schmid RM, Algül H. Treiber M, et al. Among authors: lesina m. Gastroenterology. 2011 Oct;141(4):1473-85, 1485.e1-7. doi: 10.1053/j.gastro.2011.06.087. Epub 2011 Jul 18. Gastroenterology. 2011. PMID: 21763242

9

Deletion of IκBα activates RelA to reduce acute pancreatitis in mice through up-regulation of Spi2A.

Neuhöfer P, Liang S, Einwächter H, Schwerdtfeger C, Wartmann T, Treiber M, Zhang H, Schulz HU, Dlubatz K, Lesina M, Diakopoulos KN, Wörmann S, Halangk W, Witt H, Schmid RM, Algül H. Neuhöfer P, et al. Among authors: lesina m. Gastroenterology. 2013 Jan;144(1):192-201. doi: 10.1053/j.gastro.2012.09.058. Epub 2012 Oct 3. Gastroenterology. 2013. PMID: 23041330

10

Mdm2 inhibitors synergize with topoisomerase II inhibitors to induce p53-independent pancreatic cancer cell death.

Conradt L, Henrich A, Wirth M, Reichert M, Lesina M, Algül H, Schmid RM, Krämer OH, Saur D, Schneider G. Conradt L, et al. Among authors: lesina m. Int J Cancer. 2013 May 15;132(10):2248-57. doi: 10.1002/ijc.27916. Epub 2012 Nov 26. Int J Cancer. 2013. PMID: 23115126 Free article.

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