Lescar J - Search Results

1

Defining neutralization and allostery by antibodies against COVID-19 variants.

Tulsian NK, Palur RV, Qian X, Gu Y, D/O Shunmuganathan B, Samsudin F, Wong YH, Lin J, Purushotorman K, Kozma MM, Wang B, Lescar J, Wang CI, Gupta RK, Bond PJ, MacAry PA. Tulsian NK, et al. Among authors: lescar j. Nat Commun. 2023 Nov 1;14(1):6967. doi: 10.1038/s41467-023-42408-x. Nat Commun. 2023. PMID: 37907459 Free PMC article.

2

Structure-Guided Design of an Anti-dengue Antibody Directed to a Non-immunodominant Epitope.

Robinson LN, Tharakaraman K, Rowley KJ, Costa VV, Chan KR, Wong YH, Ong LC, Tan HC, Koch T, Cain D, Kirloskar R, Viswanathan K, Liew CW, Tissire H, Ramakrishnan B, Myette JR, Babcock GJ, Sasisekharan V, Alonso S, Chen J, Lescar J, Shriver Z, Ooi EE, Sasisekharan R. Robinson LN, et al. Among authors: lescar j. Cell. 2015 Jul 30;162(3):493-504. doi: 10.1016/j.cell.2015.06.057. Epub 2015 Jul 16. Cell. 2015. PMID: 26189681 Free PMC article.

3

Functional Evolution in Orthologous Cell-encoded RNA-dependent RNA Polymerases.

Qian X, Hamid FM, El Sahili A, Darwis DA, Wong YH, Bhushan S, Makeyev EV, Lescar J. Qian X, et al. Among authors: lescar j. J Biol Chem. 2016 Apr 22;291(17):9295-309. doi: 10.1074/jbc.M115.685933. Epub 2016 Feb 23. J Biol Chem. 2016. PMID: 26907693 Free PMC article.

4

Structure of the NS2B-NS3 protease from Zika virus after self-cleavage.

Phoo WW, Li Y, Zhang Z, Lee MY, Loh YR, Tan YB, Ng EY, Lescar J, Kang C, Luo D. Phoo WW, et al. Among authors: lescar j. Nat Commun. 2016 Nov 15;7:13410. doi: 10.1038/ncomms13410. Nat Commun. 2016. PMID: 27845325 Free PMC article.

5

Engineering a Catalytically Efficient Recombinant Protein Ligase.

Yang R, Wong YH, Nguyen GKT, Tam JP, Lescar J, Wu B. Yang R, et al. Among authors: lescar j. J Am Chem Soc. 2017 Apr 19;139(15):5351-5358. doi: 10.1021/jacs.6b12637. Epub 2017 Mar 1. J Am Chem Soc. 2017. PMID: 28199119

6

Structural Mimicry of the Dengue Virus Envelope Glycoprotein Revealed by the Crystallographic Study of an Idiotype-Anti-idiotype Fab Complex.

Wong YH, Goh BC, Lim SY, Teo EW, Lim APC, Dedon PC, Hanson BJ, MacAry PA, Lescar J. Wong YH, et al. Among authors: lescar j. J Virol. 2017 Aug 10;91(17):e00406-17. doi: 10.1128/JVI.00406-17. Print 2017 Sep 1. J Virol. 2017. PMID: 28637753 Free PMC article.

7

Insights into Biofilm Dispersal Regulation from the Crystal Structure of the PAS-GGDEF-EAL Region of RbdA from Pseudomonas aeruginosa.

Liu C, Liew CW, Wong YH, Tan ST, Poh WH, Manimekalai MSS, Rajan S, Xin L, Liang ZX, Grüber G, Rice SA, Lescar J. Liu C, et al. Among authors: lescar j. J Bacteriol. 2018 Jan 10;200(3):e00515-17. doi: 10.1128/JB.00515-17. Print 2018 Feb 1. J Bacteriol. 2018. PMID: 29109186 Free PMC article.

8

The protein kinase CK2 catalytic domain from Plasmodium falciparum: crystal structure, tyrosine kinase activity and inhibition.

Ruiz-Carrillo D, Lin J, El Sahili A, Wei M, Sze SK, Cheung PCF, Doerig C, Lescar J. Ruiz-Carrillo D, et al. Among authors: lescar j. Sci Rep. 2018 May 9;8(1):7365. doi: 10.1038/s41598-018-25738-5. Sci Rep. 2018. PMID: 29743645 Free PMC article.

9

Molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody 513.

Wong YH, Kumar A, Liew CW, Tharakaraman K, Srinivasaraghavan K, Sasisekharan R, Verma C, Lescar J. Wong YH, et al. Among authors: lescar j. Sci Rep. 2018 May 31;8(1):8449. doi: 10.1038/s41598-018-26800-y. Sci Rep. 2018. PMID: 29855525 Free PMC article.

10

Targeting the Bacterial Epitranscriptome for Antibiotic Development: Discovery of Novel tRNA-(N¹G37) Methyltransferase (TrmD) Inhibitors.

Zhong W, Koay A, Ngo A, Li Y, Nah Q, Wong YH, Chionh YH, Ng HQ, Koh-Stenta X, Poulsen A, Foo K, McBee M, Choong ML, El Sahili A, Kang C, Matter A, Lescar J, Hill J, Dedon P. Zhong W, et al. Among authors: lescar j. ACS Infect Dis. 2019 Mar 8;5(3):326-335. doi: 10.1021/acsinfecdis.8b00275. Epub 2019 Feb 4. ACS Infect Dis. 2019. PMID: 30682246

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