Lerdrup M - Search Results

1

Lamin A/C impairments cause mitochondrial dysfunction by attenuating PGC1α and the NAMPT-NAD+ pathway.

Maynard S, Hall A, Galanos P, Rizza S, Yamamoto T, Gram HH, Munk SHN, Shoaib M, Sørensen CS, Bohr VA, Lerdrup M, Maya-Mendoza A, Bartek J. Maynard S, et al. Among authors: lerdrup m. Nucleic Acids Res. 2022 Sep 23;50(17):9948-9965. doi: 10.1093/nar/gkac741. Nucleic Acids Res. 2022. PMID: 36099415 Free PMC article.

2

Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing.

Shoaib M, Walter D, Gillespie PJ, Izard F, Fahrenkrog B, Lleres D, Lerdrup M, Johansen JV, Hansen K, Julien E, Blow JJ, Sørensen CS. Shoaib M, et al. Among authors: lerdrup m. Nat Commun. 2018 Sep 12;9(1):3704. doi: 10.1038/s41467-018-06066-8. Nat Commun. 2018. PMID: 30209253 Free PMC article.

3

Histone H4 lysine 20 mono-methylation directly facilitates chromatin openness and promotes transcription of housekeeping genes.

Shoaib M, Chen Q, Shi X, Nair N, Prasanna C, Yang R, Walter D, Frederiksen KS, Einarsson H, Svensson JP, Liu CF, Ekwall K, Lerdrup M, Nordenskiöld L, Sørensen CS. Shoaib M, et al. Among authors: lerdrup m. Nat Commun. 2021 Aug 20;12(1):4800. doi: 10.1038/s41467-021-25051-2. Nat Commun. 2021. PMID: 34417450 Free PMC article.

4

Proteogenomic Characterization of Patient-Derived Xenografts Highlights the Role of REST in Neuroendocrine Differentiation of Castration-Resistant Prostate Cancer.

Flores-Morales A, Bergmann TB, Lavallee C, Batth TS, Lin D, Lerdrup M, Friis S, Bartels A, Kristensen G, Krzyzanowska A, Xue H, Fazli L, Hansen KH, Røder MA, Brasso K, Moreira JM, Bjartell A, Wang Y, Olsen JV, Collins CC, Iglesias-Gato D. Flores-Morales A, et al. Among authors: lerdrup m. Clin Cancer Res. 2019 Jan 15;25(2):595-608. doi: 10.1158/1078-0432.CCR-18-0729. Epub 2018 Oct 1. Clin Cancer Res. 2019. PMID: 30274982

5

Mutant FOXL2^C134W Hijacks SMAD4 and SMAD2/3 to Drive Adult Granulosa Cell Tumors.

Weis-Banke SE, Lerdrup M, Kleine-Kohlbrecher D, Mohammad F, Sidoli S, Jensen ON, Yanase T, Nakamura T, Iwase A, Stylianou A, Abu-Rustum NR, Aghajanian C, Soslow R, Da Cruz Paula A, Koche RP, Weigelt B, Christensen J, Helin K, Cloos PAC. Weis-Banke SE, et al. Among authors: lerdrup m. Cancer Res. 2020 Sep 1;80(17):3466-3479. doi: 10.1158/0008-5472.CAN-20-0259. Epub 2020 Jul 8. Cancer Res. 2020. PMID: 32641411 Free PMC article.

6

Histone editing elucidates the functional roles of H3K27 methylation and acetylation in mammals.

Sankar A, Mohammad F, Sundaramurthy AK, Wang H, Lerdrup M, Tatar T, Helin K. Sankar A, et al. Among authors: lerdrup m. Nat Genet. 2022 Jun;54(6):754-760. doi: 10.1038/s41588-022-01091-2. Epub 2022 Jun 6. Nat Genet. 2022. PMID: 35668298

7

RAD51 protects human cells from transcription-replication conflicts.

Bhowmick R, Lerdrup M, Gadi SA, Rossetti GG, Singh MI, Liu Y, Halazonetis TD, Hickson ID. Bhowmick R, et al. Among authors: lerdrup m. Mol Cell. 2022 Sep 15;82(18):3366-3381.e9. doi: 10.1016/j.molcel.2022.07.010. Epub 2022 Aug 23. Mol Cell. 2022. PMID: 36002000 Free article.

8

JNK2 mediates TNF-induced cell death in mouse embryonic fibroblasts via regulation of both caspase and cathepsin protease pathways.

Dietrich N, Thastrup J, Holmberg C, Gyrd-Hansen M, Fehrenbacher N, Lademann U, Lerdrup M, Herdegen T, Jäättelä M, Kallunki T. Dietrich N, et al. Among authors: lerdrup m. Cell Death Differ. 2004 Mar;11(3):301-13. doi: 10.1038/sj.cdd.4401353. Cell Death Differ. 2004. PMID: 14685158

9

An interactive environment for agile analysis and visualization of ChIP-sequencing data.

Lerdrup M, Johansen JV, Agrawal-Singh S, Hansen K. Lerdrup M, et al. Nat Struct Mol Biol. 2016 Apr;23(4):349-57. doi: 10.1038/nsmb.3180. Epub 2016 Feb 29. Nat Struct Mol Biol. 2016. PMID: 26926434

10

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.

Dahl JA, Jung I, Aanes H, Greggains GD, Manaf A, Lerdrup M, Li G, Kuan S, Li B, Lee AY, Preissl S, Jermstad I, Haugen MH, Suganthan R, Bjørås M, Hansen K, Dalen KT, Fedorcsak P, Ren B, Klungland A. Dahl JA, et al. Among authors: lerdrup m. Nature. 2016 Sep 22;537(7621):548-552. doi: 10.1038/nature19360. Epub 2016 Sep 14. Nature. 2016. PMID: 27626377 Free PMC article.

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