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Identification of a novel 2-oxindole fluorinated derivative as in vivo antitumor agent for prostate cancer acting via AMPK activation.
Sci Rep. 2018 Mar 12;8(1):4370. doi: 10.1038/s41598-018-22690-2.
Sci Rep. 2018.
PMID: 29531259
Free PMC article.
Discovery and structure-activity relationships of pentanedioic acid diamides as potent inhibitors of 11beta-hydroxysteroid dehydrogenase type I.
Roche D, Carniato D, Leriche C, Lepifre F, Christmann-Franck S, Graedler U, Charon C, Bozec S, Doare L, Schmidlin F, Lecomte M, Valeur E.
Roche D, et al. Among authors: lepifre f.
Bioorg Med Chem Lett. 2009 May 15;19(10):2674-8. doi: 10.1016/j.bmcl.2009.03.140. Epub 2009 Apr 1.
Bioorg Med Chem Lett. 2009.
PMID: 19395260
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Discovery and structure-guided drug design of inhibitors of 11beta-hydroxysteroid-dehydrogenase type I based on a spiro-carboxamide scaffold.
Lepifre F, Christmann-Franck S, Roche D, Leriche C, Carniato D, Charon C, Bozec S, Doare L, Schmidlin F, Lecomte M, Valeur E.
Lepifre F, et al.
Bioorg Med Chem Lett. 2009 Jul 1;19(13):3682-5. doi: 10.1016/j.bmcl.2009.02.123. Epub 2009 Mar 5.
Bioorg Med Chem Lett. 2009.
PMID: 19450980
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Structure-based design of 7-azaindole-pyrrolidine amides as inhibitors of 11β-hydroxysteroid dehydrogenase type I.
Valeur E, Christmann-Franck S, Lepifre F, Carniato D, Cravo D, Charon C, Bozec S, Musil D, Hillertz P, Doare L, Schmidlin F, Lecomte M, Schultz M, Roche D.
Valeur E, et al. Among authors: lepifre f.
Bioorg Med Chem Lett. 2012 Sep 15;22(18):5909-14. doi: 10.1016/j.bmcl.2012.07.070. Epub 2012 Jul 31.
Bioorg Med Chem Lett. 2012.
PMID: 22901389
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Combining the use of solid-supported transition metal catalysis with microwave irradiation in solution-phase parallel library synthesis.
Organ MG, Mayer S, Lepifre F, N'Zemba B, Khatri J.
Organ MG, et al. Among authors: lepifre f.
Mol Divers. 2003;7(2-4):211-27. doi: 10.1023/b:modi.0000006826.91512.83.
Mol Divers. 2003.
PMID: 14870853
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