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Structural basis for the improved potency of peroxisome proliferator-activated receptor (PPAR) agonists.
ChemMedChem. 2010 Oct 4;5(10):1707-16. doi: 10.1002/cmdc.201000194.
ChemMedChem. 2010.
PMID: 20734309
Structure-based drug design of novel Aurora kinase A inhibitors: structural basis for potency and specificity.
Coumar MS, Leou JS, Shukla P, Wu JS, Dixit AK, Lin WH, Chang CY, Lien TW, Tan UK, Chen CH, Hsu JT, Chao YS, Wu SY, Hsieh HP.
Coumar MS, et al. Among authors: leou js.
J Med Chem. 2009 Feb 26;52(4):1050-62. doi: 10.1021/jm801270e.
J Med Chem. 2009.
PMID: 19140666
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Identification, SAR studies, and X-ray co-crystallographic analysis of a novel furanopyrimidine aurora kinase A inhibitor.
Coumar MS, Tsai MT, Chu CY, Uang BJ, Lin WH, Chang CY, Chang TY, Leou JS, Teng CH, Wu JS, Fang MY, Chen CH, Hsu JT, Wu SY, Chao YS, Hsieh HP.
Coumar MS, et al. Among authors: leou js.
ChemMedChem. 2010 Feb 1;5(2):255-67. doi: 10.1002/cmdc.200900339.
ChemMedChem. 2010.
PMID: 20039358
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Aurora kinase A inhibitors: identification, SAR exploration and molecular modeling of 6,7-dihydro-4H-pyrazolo-[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-dione scaffold.
Coumar MS, Wu JS, Leou JS, Tan UK, Chang CY, Chang TY, Lin WH, Hsu JT, Chao YS, Wu SY, Hsieh HP.
Coumar MS, et al. Among authors: leou js.
Bioorg Med Chem Lett. 2008 Mar 1;18(5):1623-7. doi: 10.1016/j.bmcl.2008.01.068. Epub 2008 Jan 19.
Bioorg Med Chem Lett. 2008.
PMID: 18243698
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Fast-forwarding hit to lead: aurora and epidermal growth factor receptor kinase inhibitor lead identification.
Coumar MS, Chu CY, Lin CW, Shiao HY, Ho YL, Reddy R, Lin WH, Chen CH, Peng YH, Leou JS, Lien TW, Huang CT, Fang MY, Wu SH, Wu JS, Chittimalla SK, Song JS, Hsu JT, Wu SY, Liao CC, Chao YS, Hsieh HP.
Coumar MS, et al. Among authors: leou js.
J Med Chem. 2010 Jul 8;53(13):4980-8. doi: 10.1021/jm1000198.
J Med Chem. 2010.
PMID: 20550212
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Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity.
Chiang YK, Kuo CC, Wu YS, Chen CT, Coumar MS, Wu JS, Hsieh HP, Chang CY, Jseng HY, Wu MH, Leou JS, Song JS, Chang JY, Lyu PC, Chao YS, Wu SY.
Chiang YK, et al. Among authors: leou js.
J Med Chem. 2009 Jul 23;52(14):4221-33. doi: 10.1021/jm801649y.
J Med Chem. 2009.
PMID: 19507860
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Protein-arginine methyltransferase 1 suppresses megakaryocytic differentiation via modulation of the p38 MAPK pathway in K562 cells.
Chang YI, Hua WK, Yao CL, Hwang SM, Hung YC, Kuan CJ, Leou JS, Lin WJ.
Chang YI, et al. Among authors: leou js.
J Biol Chem. 2010 Jul 2;285(27):20595-606. doi: 10.1074/jbc.M109.092411. Epub 2010 May 4.
J Biol Chem. 2010.
PMID: 20442406
Free PMC article.
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Cellulose-based diagnostic devices for diagnosing serotype-2 dengue fever in human serum.
Wang HK, Tsai CH, Chen KH, Tang CT, Leou JS, Li PC, Tang YL, Hsieh HJ, Wu HC, Cheng CM.
Wang HK, et al. Among authors: leou js.
Adv Healthc Mater. 2014 Feb;3(2):187-96. doi: 10.1002/adhm.201300150. Epub 2013 Jul 11.
Adv Healthc Mater. 2014.
PMID: 23843297
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