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A conformational rearrangement of the SARS-CoV-2 host protein sigma-1 is required for antiviral activity: insights from a combined in-silico/in-vitro approach.
Abatematteo FS, Delre P, Mercurio I, Rezelj VV, Siliqi D, Beaucourt S, Lattanzi G, Colabufo NA, Leopoldo M, Saviano M, Vignuzzi M, Mangiatordi GF, Abate C. Abatematteo FS, et al. Among authors: leopoldo m. Sci Rep. 2023 Aug 7;13(1):12798. doi: 10.1038/s41598-023-39662-w. Sci Rep. 2023. PMID: 37550340 Free PMC article.
Rescue of prepulse inhibition deficit and brain mitochondrial dysfunction by pharmacological stimulation of the central serotonin receptor 7 in a mouse model of CDKL5 Deficiency Disorder.
Vigli D, Rusconi L, Valenti D, La Montanara P, Cosentino L, Lacivita E, Leopoldo M, Amendola E, Gross C, Landsberger N, Laviola G, Kilstrup-Nielsen C, Vacca RA, De Filippis B. Vigli D, et al. Among authors: leopoldo m. Neuropharmacology. 2019 Jan;144:104-114. doi: 10.1016/j.neuropharm.2018.10.018. Epub 2018 Oct 13. Neuropharmacology. 2019. PMID: 30326240 Free article.
Activation of 5-HT7 serotonin receptors reverses metabotropic glutamate receptor-mediated synaptic plasticity in wild-type and Fmr1 knockout mice, a model of Fragile X syndrome.
Costa L, Spatuzza M, D'Antoni S, Bonaccorso CM, Trovato C, Musumeci SA, Leopoldo M, Lacivita E, Catania MV, Ciranna L. Costa L, et al. Among authors: leopoldo m. Biol Psychiatry. 2012 Dec 1;72(11):924-33. doi: 10.1016/j.biopsych.2012.06.008. Epub 2012 Jul 18. Biol Psychiatry. 2012. PMID: 22817866
156 results