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NTAL is associated with treatment outcome, cell proliferation and differentiation in acute promyelocytic leukemia.
Thomé CH, Ferreira GA, Pereira-Martins DA, Dos Santos GA, Ortiz CA, de Souza LEB, Sobral LM, Silva CLA, Scheucher PS, Gil CD, Leopoldino AM, Silveira DRA, Coelho-Silva JL, Traina F, Koury LC, Melo RAM, Bittencourt R, Pagnano K, Pasquini R, Nunes EC, Fagundes EM, Gloria ABF, Kerbauy FR, Chauffaille ML, Keating A, Tallman MS, Ribeiro RC, Dillon R, Ganser A, Löwenberg B, Valk P, Lo-Coco F, Sanz MA, Berliner N, Faça VM, Rego EM. Thomé CH, et al. Among authors: leopoldino am. Sci Rep. 2020 Jun 25;10(1):10315. doi: 10.1038/s41598-020-66223-2. Sci Rep. 2020. PMID: 32587277 Free PMC article.
Linker for activation of T-cell family member2 (LAT2) a lipid raft adaptor protein for AKT signaling, is an early mediator of alkylphospholipid anti-leukemic activity.
Thomé CH, dos Santos GA, Ferreira GA, Scheucher PS, Izumi C, Leopoldino AM, Simão AM, Ciancaglini P, de Oliveira KT, Chin A, Hanash SM, Falcão RP, Rego EM, Greene LJ, Faça VM. Thomé CH, et al. Among authors: leopoldino am. Mol Cell Proteomics. 2012 Dec;11(12):1898-912. doi: 10.1074/mcp.M112.019661. Epub 2012 Sep 22. Mol Cell Proteomics. 2012. PMID: 23001822 Free PMC article.
Proteomic approaches identify members of cofilin pathway involved in oral tumorigenesis.
Polachini GM, Sobral LM, Mercante AM, Paes-Leme AF, Xavier FC, Henrique T, Guimarães DM, Vidotto A, Fukuyama EE, Góis-Filho JF, Cury PM, Curioni OA, Michaluart P Jr, Silva AM, Wünsch-Filho V, Nunes FD, Leopoldino AM, Tajara EH. Polachini GM, et al. Among authors: leopoldino am. PLoS One. 2012;7(12):e50517. doi: 10.1371/journal.pone.0050517. Epub 2012 Dec 5. PLoS One. 2012. PMID: 23227181 Free PMC article.
Stable SET knockdown in head and neck squamous cell carcinoma promotes cell invasion and the mesenchymal-like phenotype in vitro, as well as necrosis, cisplatin sensitivity and lymph node metastasis in xenograft tumor models.
Sobral LM, Sousa LO, Coletta RD, Cabral H, Greene LJ, Tajara EH, Gutkind JS, Curti C, Leopoldino AM. Sobral LM, et al. Among authors: leopoldino am. Mol Cancer. 2014 Feb 20;13:32. doi: 10.1186/1476-4598-13-32. Mol Cancer. 2014. PMID: 24555657 Free PMC article.
The lipid raft protein NTAL participates in AKT signaling in mantle cell lymphoma.
Ferreira GA, Thomé CH, Simão AMS, Scheucher PS, Silva CLA, Chahud F, Ciancaglini P, Leopoldino AM, Rego EM, Faça VM, Dos Santos GA. Ferreira GA, et al. Among authors: leopoldino am. Leuk Lymphoma. 2019 Nov;60(11):2658-2668. doi: 10.1080/10428194.2019.1607326. Epub 2019 May 7. Leuk Lymphoma. 2019. PMID: 31060403
74 results